Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Premature separation of placenta
ADR ID BADD_A03541
ADR Hierarchy
18      Pregnancy, puerperium and perinatal conditions
18.02      Maternal complications of pregnancy
18.02.01      Haemorrhagic complications of pregnancy
18.02.01.004      Premature separation of placenta
24      Vascular disorders
24.07      Vascular haemorrhagic disorders
24.07.03      Reproductive system haemorrhages
24.07.03.019      Premature separation of placenta
Description Premature separation of the normally implanted PLACENTA from the UTERUS. Signs of varying degree of severity include UTERINE BLEEDING, uterine MUSCLE HYPERTONIA, and FETAL DISTRESS or FETAL DEATH. [MeSH]
MedDRA Code 10036608
MeSH ID D000037
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Abruptio placentae | Premature separation of placenta | Premature separation of placenta, antepartum | Premature separation of placenta, unspecified as to episode of care | Premature separation of placenta, with delivery | Premature placental detachment | Couvelaire uterus | Uteroplacental apoplexy | Abruptio Placentae | Placental Abruption | Abruption, Placental | Abruptions, Placental | Placental Abruptions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00312Bupropion--
BADD_D00329Cabergoline0.004804%
BADD_D00623Dexamethasone0.000145%
BADD_D00680Dimethyl fumarate0.000400%
BADD_D00684Dinoprostone0.000366%
BADD_D00932Fluoxetine0.000079%
BADD_D01107Hydroxyprogesterone caproate-
BADD_D01243Lamotrigine0.000055%
BADD_D01257Letrozole0.000263%
BADD_D01265Levetiracetam0.000238%
BADD_D01281Levonorgestrel0.002128%
BADD_D01285Levothyroxine0.000005%
BADD_D01366Medroxyprogesterone acetate0.000119%
BADD_D01425Methyldopa0.002567%
BADD_D01476Mirtazapine0.000080%
BADD_D01477Misoprostol0.002158%
BADD_D01496Montelukast0.000015%
BADD_D01564Nicotine0.000940%
BADD_D01566Nifedipine0.000187%
BADD_D01831Prednisolone0.000035%
BADD_D01852Progesterone0.000439%
BADD_D01951Risperidone0.000121%
BADD_D02105Tacrolimus0.000594%
BADD_D02464Fingolimod0.000241%
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