Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Otitis externa
ADR ID BADD_A03228
ADR Hierarchy
04      Ear and labyrinth disorders
04.01      External ear disorders (excl congenital)
04.01.02      External ear infections and inflammations
04.01.02.001      Otitis externa
11      Infections and infestations
11.01      Infections - pathogen unspecified
11.01.05      Ear infections
11.01.05.003      Otitis externa
Description A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage. [CTCAE] Inflammation of the OUTER EAR including the external EAR CANAL, cartilages of the auricle (EAR CARTILAGE), and the TYMPANIC MEMBRANE. [MeSH]
MedDRA Code 10033072
MeSH ID D010032
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute infection of pinna | Acute swimmers' ear | Bilateral otitis externa | External ear infection NOS | Infection of the outer ear | Infective otitis externa | Infective otitis externa, unspecified | Left otitis externa | Malignant otitis externa | Other acute infections of external ear | Other acute otitis externa | Other chronic infective otitis externa | Other chronic otitis externa | Other otitis externa | Otitis externa | Otitis externa (excl boil of meatus) | Otitis externa (excl boil of meatus) NOS | Right otitis externa | Otitis externa NOS | Necrotizing otitis externa | Necrotising otitis externa | Otitis Externa | Externa, Otitis | External Otitis | External Otitides | Otitides, External | Otitis, External
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin--
BADD_D00066Alendronic acid0.000505%
BADD_D00165Aripiprazole--
BADD_D00269Bexarotene--
BADD_D00285Bosentan0.000447%
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00471Ciprofloxacin--
BADD_D00474Cisplatin0.000799%
BADD_D00623Dexamethasone0.001030%
BADD_D00706Donepezil--
BADD_D00707Donepezil hydrochloride--
BADD_D00790Eprosartan--
BADD_D00791Eprosartan mesylate--
BADD_D00809Escitalopram--
BADD_D00837Eszopiclone--
BADD_D00981Gabapentin--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01162Insulin detemir--
BADD_D01378Memantine--
BADD_D01507Mycophenolate mofetil--
BADD_D01567Nilotinib0.000533%
BADD_D01598Ofloxacin--
BADD_D01617Ondansetron0.000350%
BADD_D01637Oxcarbazepine--
BADD_D01668Pantoprazole--
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
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