Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Eprosartan mesylate
Drug ID BADD_D00791
Description Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Indications and Usage For the management of hypertension alone or in combination with other classes of antihypertensive agents. Also used as a first-line agent in the treatment of diabetic nephropathy, as well as a second-line agent in the treatment of congestive heart failure (only in those intolerant of ACE inhibitors).
Marketing Status Not Available
ATC Code C09CA02
DrugBank ID DB00876
KEGG ID D02082
MeSH ID C401803
PubChem ID 5282474
TTD Drug ID Not Available
NDC Product Code 65372-1142; 64220-108; 50370-0020; 53747-021
Synonyms eprosartan mesylate dihydrate | epro-sartan mesylate dihydrate
Chemical Information
Molecular Formula C24H28N2O7S2
CAS Registry Number 144143-96-4
SMILES CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)C=C(CC3=CC=CS3)C(=O)O.CS(=O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Alanine aminotransferase increased13.03.01.003--
Albuminuria20.02.01.001--Not Available
Alcohol intolerance14.02.01.001--
Anaemia01.03.02.001--
Angina pectoris24.04.04.002; 02.02.02.002--
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Atrial fibrillation02.03.03.002--
Back pain15.03.04.005--
Blood creatine phosphokinase increased13.04.01.001--
Bone pain15.02.01.001--
Bradycardia02.03.02.002--Not Available
Chest pain08.01.08.002; 02.02.02.011; 22.02.08.003--Not Available
Chills15.05.03.016; 08.01.09.001--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Cough22.02.03.001--
Cystitis20.03.02.002; 11.01.14.001--
Depression19.15.01.001--
Diabetes mellitus14.06.01.001; 05.06.01.001--Not Available
Dry mouth07.06.01.002--
Eczema23.03.04.006--
Electrocardiogram abnormal13.14.05.001--Not Available
Epistaxis24.07.01.005; 22.04.03.001--
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