Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Kyphosis
ADR ID BADD_A02458
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.10      Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)
15.10.04      Spine and neck deformities
15.10.04.002      Kyphosis
Description A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine. [CTCAE] Deformities of the SPINE characterized by an exaggerated convexity of the vertebral column. The forward bending of the thoracic region usually is more than 40 degrees. This deformity sometimes is called round back or hunchback. [MeSH]
MedDRA Code 10023509
MeSH ID D007738
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Adolescent postural kyphosis | Hunchback (acquired) | Kyphosis | Kyphosis (acquired) | Kyphosis (acquired) (postural) | Kyphosis associated with other conditions | Other kyphosis, acquired | Cervical kyphosis | Hyperkyphosis | Thoracic kyphosis | Thoracolumbar kyphosis | Reverse cervical lordosis | Kyphoses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00044Adefovir dipivoxil0.000282%
BADD_D00066Alendronic acid0.000704%
BADD_D00165Aripiprazole--
BADD_D00981Gabapentin0.000026%
BADD_D01242Lamivudine0.001012%
BADD_D01418Methotrexate0.000580%
BADD_D01433Methylprednisolone0.000070%
BADD_D01496Montelukast--
BADD_D01831Prednisolone0.000070%
BADD_D01835Pregabalin0.000114%
BADD_D02236Tofacitinib0.001640%
BADD_D02329Valproic acid0.000449%
BADD_D02346Venlafaxine0.000032%
BADD_D02392Zoledronic acid--
BADD_D02434Cinacalcet0.000391%
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ADReCS-Target
ADR Term Drug Name Target