Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cinacalcet
Drug ID BADD_D02434
Description Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Indications and Usage For the treatment of secondary hyperparathyroidism in patients with Chronic Kidney Disease who are on hemodialysis or peritoneal dialysis. Also for the treatment of hypercalcemia in patients with parathyroid carcinoma.
Marketing Status Not Available
ATC Code H05BX01
DrugBank ID DB01012
KEGG ID D03504
MeSH ID D000069449
PubChem ID 156419
TTD Drug ID D03YGR
NDC Product Code 51407-297; 43598-368; 42291-461; 72865-152; 50268-153; 47335-379; 42291-459; 65162-213; 16714-079; 31722-104; 63629-8763; 42291-460; 64380-885; 67877-505; 68180-227; 68180-228; 72865-151; 65162-155; 16729-440; 63629-8765; 43598-367; 31722-103; 16714-080; 31722-105; 16729-441; 69097-410; 60687-525; 69097-412; 16714-078; 65862-831; 72865-150; 65862-833; 47335-380; 69097-411; 47335-600; 76282-676; 51407-296; 42543-961; 0904-7067; 65862-832; 76282-674; 64380-883; 64380-884; 42543-962; 43598-369; 51407-295; 67877-503; 67877-504; 42543-963; 68180-226; 76282-675; 65162-157; 63629-8764; 16729-442
Synonyms Cinacalcet | Cinacalcet Hydrochloride | Alpha-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-naphthalenemethanamine, (alphaR)-hydrochloride | Sensipar | AMG 073 | KRN 1493 | AMG073
Chemical Information
Molecular Formula C22H22F3N
CAS Registry Number 226256-56-0
SMILES CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.373563%Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.0030.252625%
Abdominal rigidity07.01.05.0110.001792%Not Available
Abnormal sensation in eye06.01.01.0010.001792%Not Available
Abortion spontaneous18.01.04.001--Not Available
Abscess11.01.08.001--Not Available
Acne23.02.01.001--Not Available
Ageusia17.02.07.001; 07.14.03.003--Not Available
Aggression19.05.01.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Alopecia23.02.02.001--
Altered state of consciousness19.07.01.003; 17.02.04.001--Not Available
Ammonia increased13.03.01.023--Not Available
Amnesia19.20.01.001; 17.03.02.001--
Anaemia01.03.02.001--
Anger19.04.02.001--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Ankle fracture15.08.03.005; 12.04.01.005--
Anxiety19.06.02.002--
Aphonia22.02.05.024; 19.19.01.002; 17.02.08.009--
Arrhythmia02.03.02.0010.062708%Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Arthropathy15.01.01.003--Not Available
Ascites09.01.05.003; 07.07.01.001; 02.05.04.002--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrial fibrillation02.03.03.002--
The 1th Page    1 2 3 4 5    Next   Last    Total 17 Pages