| ADR Ontology |
| ADR Term |
Kaposi's sarcoma |
| ADR ID |
BADD_A02437 |
| ADR Hierarchy |
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| Description |
A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause. [MeSH] |
| MedDRA Code |
10023284 |
| MeSH ID |
D012514
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Allograft-associated hemorrhagic sarcoma | Endemic type hemorrhagic sarcoma | Idiopathic haemorrhagic sarcoma | Kaposi's sarcoma | Kaposi's sarcoma NOS | Kaposi's sarcoma, gastrointestinal sites | Kaposi's sarcoma, lung | Kaposi's sarcoma, lymph nodes | Kaposi's sarcoma, other specified sites | Kaposi's sarcoma, palate | Kaposi's sarcoma, skin | Kaposi's sarcoma, soft tissue | Kaposi's sarcoma, unspecified | Multiple haemorrhagic sarcoma | Multiple hemorrhagic sarcoma | Multiple idiopathic hemorrhagic sarcoma | Idiopathic hemorrhagic sarcoma | Allograft-associated haemorrhagic sarcoma | Endemic type haemorrhagic sarcoma | Multiple idiopathic haemorrhagic sarcoma | Sarcoma, Kaposi | Kaposi's Sarcoma | Kaposis Sarcoma | Sarcoma, Kaposi's | Multiple Idiopathic Pigmented Hemangiosarcoma | Kaposi Sarcoma |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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