Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01779Piperacillin--
BADD_D01780Piperacillin sodium--
BADD_D01781Pirbuterol--
BADD_D01782Pirbuterol acetate--
BADD_D01783Pirfenidone0.091020%
BADD_D01785Pitavastatin calcium--
BADD_D01786Pixantrone--
BADD_D01787Pizotyline--
BADD_D01788Plerixafor0.003951%
BADD_D01789Plerixafor octahydrochloride--
BADD_D01798Pomalidomide0.556343%
BADD_D01799Ponatinib0.002865%
BADD_D01800Ponatinib hydrochloride--
BADD_D01802Porfimer--
BADD_D01803Porfimer sodium--
BADD_D01804Posaconazole--
BADD_D01812Potassium phosphate monobasic--
BADD_D01814Pralatrexate--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01819Pramlintide--
BADD_D01820Pramlintide acetate--
BADD_D01822Prasugrel--
BADD_D01823Prasugrel hydrochloride--
BADD_D01824Pravastatin--
BADD_D01825Pravastatin sodium--
BADD_D01826Praziquantel--
BADD_D01827Prazosin0.000338%
BADD_D01833Prednisolone sodium phosphate--
BADD_D01834Prednisone--
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ADReCS-Target
ADR Term Drug Name Target