Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Praziquantel
Drug ID BADD_D01826
Description An anthelmintic used in most schistosome and many cestode infestations.
Indications and Usage For the treatment of infections due to all species of schistosoma.
Marketing Status Prescription
ATC Code P02BA01
DrugBank ID DB01058
KEGG ID D00471
MeSH ID D011223
PubChem ID 4891
TTD Drug ID D0L9ZR
NDC Product Code 69011-0001; 86055-0003; 13371-321; 49452-5976; 38779-0090; 53104-7567; 71052-203; 12527-2521; 72643-005; 51927-2737; 14639-0022; 49884-231; 52562-022; 10745-0422; 50419-747; 62991-2053; 49169-1027
Synonyms Praziquantel | Prasiquantel | Praziquantel, (+-)-Isomer | Praziquantel, (R)-Isomer | Praziquantel, (S)-Isomer | Drontsit | Traziquantel | Biltricide | Cesol | Cysticide | Cisticid | Droncit | EMBAY 8440 | Pyquiton
Chemical Information
Molecular Formula C19H24N2O2
CAS Registry Number 55268-74-1
SMILES C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.0020.007503%
Anaphylactic reaction10.01.07.001; 24.06.03.0060.007503%
Anaphylactic shock24.06.02.004; 10.01.07.0020.007503%Not Available
Arrhythmia02.03.02.001--Not Available
Ascites09.01.05.003; 07.07.01.001; 02.05.04.0020.007503%
Asthenia08.01.01.001--Not Available
Atrioventricular block02.03.01.002--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Bradycardia02.03.02.002--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Diarrhoea haemorrhagic24.07.02.004; 07.02.01.002--Not Available
Discomfort08.01.08.003--Not Available
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.0070.011254%
Dyspnoea22.02.01.004; 02.01.03.0020.007503%
Eosinophilia01.02.04.0010.011254%
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.0280.007503%
Hypersensitivity10.01.03.003--
Immune system disorder10.02.01.001--Not Available
Malaise08.01.01.003--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
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