| Drug Name |
Pravastatin sodium |
| Drug ID |
BADD_D01825 |
| Description |
Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin].[T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co. Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved in 1991.[L6142]
Pravastatin is made through a fermentation process in which [mevastatin] is first obtained. The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation with _Streptomyces carbophilus_ to introduce the allylic 6-alcohol group.[T239] |
| Indications and Usage |
For the treatment of hypercholesterolemia and to reduce the risk of cardiovascular disease. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
C10AA03 |
| DrugBank ID |
DB00175
|
| KEGG ID |
D00893
|
| MeSH ID |
D017035
|
| PubChem ID |
16759173
|
| TTD Drug ID |
D02RQU
|
| NDC Product Code |
50090-3258; 68180-487; 35356-919; 61919-801; 71205-516; 65862-635; 65862-633; 0615-8030; 50268-668; 70377-046; 68462-198; 68382-071; 68382-072; 63629-7086; 65841-739; 70377-048; 60687-169; 55154-7275; 60505-0170; 63629-8911; 70377-045; 63629-9162; 70518-1157; 68071-5001; 65862-634; 72189-060; 71335-0692; 0615-8410; 65862-632; 61919-731; 68071-3361; 0093-7202; 68462-197; 68180-485; 43063-143; 60505-1323; 60505-0168; 71610-637; 50090-4206; 68071-4707; 16729-009; 70518-2505; 70518-2887; 0904-5892; 50090-3853; 72189-059; 68180-488; 61919-708; 63629-9164; 68071-4039; 51079-458; 55154-5370; 50090-5927; 57237-165; 0904-5891; 50268-666; 55111-274; 0615-8029; 70934-161; 71205-294; 82009-007; 35356-921; 70934-832; 72789-143; 63187-415; 60687-190; 16729-011; 70518-2986; 71335-0947; 57237-167; 51846-1022; 16729-010; 55154-5365; 50268-665; 68071-3358; 35356-125; 58623-0123; 0093-7201; 60760-421; 82009-006; 68382-073; 63629-8910; 60505-0169; 63629-8904; 72789-161; 71335-1243; 55111-231; 60687-178; 63629-8905; 63629-8913; 68462-195; 68382-070; 61919-546; 61919-707; 50090-5809; 65841-740; 0093-0771; 63187-732; 42291-665; 55111-229; 51079-782; 72189-119; 50090-2024; 43353-964; 70377-047; 42291-669; 63629-7508; 72189-061; 70518-2229; 0904-5893; 68071-3247; 57237-166; 55111-230; 82009-008; 63629-8912; 50268-667; 68180-486; 70518-1938; 68462-196; 63629-8909; 71335-0056; 43063-443; 43063-807; 63629-9165; 65841-741; 16729-008; 0093-7270; 63629-8835; 65727-003; 71205-149; 68071-3366; 68254-0004; 60760-422; 63629-4588; 70518-0549; 63629-8836; 43063-808; 63629-8906; 70934-236; 70518-0876; 63187-413; 71335-0101; 61919-709; 63629-8833; 68071-5007; 57237-164; 42291-667; 50090-2025; 50090-3898; 65841-742; 43353-966; 55154-7998; 63629-9163; 71205-121; 43063-444; 68071-4894; 71335-1022; 50090-3204; 42291-668; 63187-731; 0615-8159 |
| Synonyms |
Pravastatin | Eptastatin | Vasten | CS-514 | CS 514 | CS514 | Lin-Pravastatin | Lin Pravastatin | Lipemol | Liplat | Nu-Pravastatin | Nu Pravastatin | Prareduct | Mevalotin | Pravachol | Elisor | Selektine | Lipostat | Pravacol | Pravasin | Pravastatin Monosodium Salt, (6 beta)-Isomer | Pravastatin Sodium | Pravastatin Sodium Salt | Sodium Salt, Pravastatin | Pravastatin tert-Octylamine Salt | Pravastatin tert Octylamine Salt | Pravastatin, (6 beta)-Isomer | RMS-431 | RMS 431 | RMS431 | SQ-31000 | SQ 31000 | SQ31000 | SQ-31,000 | SQ 31,000 | SQ31,000 | Apo-Pravastatin | Apo Pravastatin | Bristacol |
