Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00812Eslicarbazepine acetate--
BADD_D00813Esmolol--
BADD_D00814Esmolol hydrochloride--
BADD_D00815Esomeprazole--
BADD_D00816Esomeprazole magnesium--
BADD_D00817Esomeprazole sodium--
BADD_D00818Esomeprazole strontium--
BADD_D00821Estradiol--
BADD_D00825Estradiol valerate--
BADD_D00835Estrone sulfate--
BADD_D00839Ethacrynate sodium--
BADD_D00840Ethacrynic acid--
BADD_D00846Ethosuximide--
BADD_D00847Ethotoin--
BADD_D00850Etodolac0.000755%
BADD_D00852Etonogestrel--
BADD_D00853Etophos--
BADD_D00854Etoposide--
BADD_D00856Etoricoxib--
BADD_D00857Etravirine--
BADD_D00858Everolimus0.075525%
BADD_D00859Evolocumab--
BADD_D00861Exemestane0.042140%
BADD_D00863Extendin-4--
BADD_D00864Ezetimibe--
BADD_D00865Ezogabine--
BADD_D00868Famciclovir--
BADD_D00869Famotidine--
BADD_D00870Febuxostat--
BADD_D00871Felbamate--
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ADReCS-Target
ADR Term Drug Name Target