Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Famciclovir
Drug ID BADD_D00868
Description Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Indications and Usage For the treatment of acute herpes zoster (shingles). Also for the treatment or suppression of recurrent genital herpes in immunocompetent patients and treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.
Marketing Status Prescription; Discontinued
ATC Code J05AB09; S01AD07
DrugBank ID DB00426
KEGG ID D00317
MeSH ID D000077595
PubChem ID 3324
TTD Drug ID D0VT8P
NDC Product Code 64980-350; 33342-024; 42291-416; 60505-3247; 63187-919; 31722-706; 16714-615; 65862-466; 16714-616; 65977-0047; 60429-361; 63187-998; 60429-359; 17856-0705; 63629-7890; 65862-465; 31722-707; 65862-486; 64980-349; 72969-027; 60505-3246; 0093-8118; 71205-609; 16714-614; 0093-8119; 17856-0706; 53104-7616; 65862-467; 55289-168; 60429-360; 33342-026; 33342-025; 63187-920; 71052-199; 60505-3245; 42291-415; 31722-708; 17856-0708; 69875-8015; 0093-8117; 42291-414; 64980-351
Synonyms Famciclovir | 9-(4-Acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine | 1,3-Propanediol, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-, diacetate (ester) | BRL 42810 | BRL-42810 | BRL42810 | Famvir
Chemical Information
Molecular Formula C14H19N5O4
CAS Registry Number 104227-87-4
SMILES CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Alanine aminotransferase13.03.01.031--Not Available
Amylase13.05.01.010--Not Available
Anaemia01.03.02.001--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Aspartate aminotransferase13.03.01.032--Not Available
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Blood bilirubin13.03.01.040--Not Available
Blood creatine phosphokinase increased13.04.01.001--
Blood creatinine13.13.01.020--Not Available
Body temperature increased13.15.01.001--Not Available
Chills08.01.09.001; 15.05.03.016--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Delirium19.13.02.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Disorientation17.02.05.015; 19.13.01.002--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dysmenorrhoea21.01.01.002--
Dyspepsia07.01.02.001--
Enzyme abnormality14.11.01.015--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Eyelid oedema23.04.01.003; 10.01.05.001; 06.04.04.004--Not Available
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