Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ethosuximide
Drug ID BADD_D00846
Description An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Indications and Usage For the treatment of petit mal epilepsy.
Marketing Status Prescription
ATC Code N03AD01
DrugBank ID DB00593
KEGG ID D00539
MeSH ID D005013
PubChem ID 3291
TTD Drug ID D0Q4XQ
NDC Product Code 61748-025; 64380-878; 10888-8169; 49452-2803; 69452-152; 71335-1763; 0071-0237; 0071-2418; 42806-711; 63629-8005; 51927-3436; 59762-2350; 11014-0047; 17349-0006; 59762-2250; 0121-0670; 23155-532
Synonyms Ethosuximide | Ethosuccimid | Ethylmethylsuccimide | Ethymal | Zarontin | Petnidan | Pyknolepsinum | Suksilep | Suxilep | Emeside | Etosuximida Faes | Faes, Etosuximida
Chemical Information
Molecular Formula C7H11NO2
CAS Registry Number 77-67-8
SMILES CCC1(CC(=O)NC1=O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.0020.019368%
Abdominal pain upper07.01.05.003--
Aggression19.05.01.0010.019368%Not Available
Agitation19.06.02.001; 17.02.05.0120.019368%
Agranulocytosis01.02.03.001--Not Available
Aplastic anaemia01.03.03.0020.005053%Not Available
Arthralgia15.01.02.0010.019368%
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Depression19.15.01.001--
Depression suicidal19.15.01.004--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Disturbance in attention19.21.02.002; 17.03.03.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.015--Not Available
Drug hypersensitivity10.01.01.0010.019368%Not Available
Dysphagia07.01.06.0030.048420%
Eosinophilia01.02.04.001--
Epilepsy17.12.03.0020.029052%Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Euphoric mood19.04.02.006--
Eye disorder06.08.03.001--Not Available
Fatigue08.01.01.002--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Generalised tonic-clonic seizure17.12.01.0020.019368%Not Available
Gingival hypertrophy07.09.03.006--Not Available
Haematuria20.02.01.006; 24.07.01.047--
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