Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etodolac
Drug ID BADD_D00850
Description Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Indications and Usage For acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.
Marketing Status Prescription; Discontinued
ATC Code M01AB08
DrugBank ID DB00749
KEGG ID D00315
MeSH ID D017308
PubChem ID 3308
TTD Drug ID D0N1WU
NDC Product Code 51655-423; 60760-378; 17373-1086; 61919-251; 71335-0126; 43353-918; 51672-4051; 63629-1935; 63187-374; 43063-834; 0185-0687; 55700-592; 63629-8805; 57451-1161; 60429-312; 71335-0982; 50090-3974; 60505-0040; 43353-749; 43063-578; 43063-856; 70518-3116; 55700-757; 60429-244; 60429-315; 43353-753; 71335-0399; 61919-092; 71205-467; 51672-4052; 66267-575; 63187-796; 60760-552; 71335-0602; 68788-7315; 76385-118; 68382-272; 61919-784; 68382-271; 70518-3163; 60429-314; 43353-752; 62559-251; 50090-3963; 68382-273; 60505-0039; 0093-1118; 63187-736; 60429-313; 69238-1342; 63629-8598; 65841-779; 42291-405; 43063-671; 62559-250; 63187-793; 50090-0613; 50090-1789; 42291-404; 42799-111; 80425-0140; 35356-711; 63629-3641; 51672-4018; 70934-282; 63629-1936; 43353-294; 60429-311; 69238-1343; 51672-4053; 60429-243; 50090-4053; 65841-778; 71335-1958; 68788-7300; 80425-0181; 60505-0041; 51672-4036; 80425-0126; 12658-0580; 16714-499; 65841-777; 0093-1122; 60760-298; 51672-4016; 50090-2133; 71205-140; 16714-498; 16714-497; 51672-4017; 50090-1790; 71335-1230; 67296-1271; 69306-020; 17373-1087; 58793-010; 42799-112; 61919-858; 0185-0675; 67628-1001; 0093-7172; 60505-0102; 76385-119
Synonyms Etodolac | Etodolic Acid | Etodolac, (+-)-Isomer | Etodolac, (-)-Isomer | Etodolac, (S)-Isomer | Ultradol | Etodolac, Monosodium Salt, (+-) Isomer | Etodolac, Monosodium Salt, (S)-Isomer | Lodine | Ramodar | AY-24,236 | AY 24,236 | AY-24236 | AY 24236 | Etodolac, Monosodium Salt
Chemical Information
Molecular Formula C17H21NO3
CAS Registry Number 41340-25-4
SMILES CCC1=C2C(=CC=C1)C3=C(N2)C(OCC3)(CC)CC(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.0020.001484%
Abdominal pain upper07.01.05.003--
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Abnormal faeces07.01.03.001--Not Available
Acute hepatic failure09.01.03.0010.000989%Not Available
Acute respiratory distress syndrome22.01.03.0010.000258%
Ageusia17.02.07.001; 07.14.03.003--Not Available
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Anaemia01.03.02.0010.001978%
Anaphylactic reaction24.06.03.006; 10.01.07.0010.001484%
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Aplastic anaemia01.03.03.002--Not Available
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.0010.000989%
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Bladder pain20.02.02.001--Not Available
Bleeding time prolonged13.01.02.002--Not Available
Blood creatinine increased13.13.01.0040.000989%
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bronchitis11.01.09.001; 22.07.01.001--
Bronchospasm22.03.01.004; 10.01.03.012--
Burning sensation17.02.06.001; 08.01.09.029--Not Available
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