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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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Drug ID
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ADR Ontology
ADR Term
Exostosis
ADR ID
BADD_A01561
ADR Hierarchy
15
Musculoskeletal and connective tissue disorders
15.02
Bone disorders (excl congenital and fractures)
15.02.04
Bone disorders NEC
15.02.04.005
Exostosis
Description
A disorder characterized by non-neoplastic overgrowth of bone. [CTCAE] Benign hypertrophy that projects outward from the surface of bone, often containing a cartilaginous component. [MeSH]
MedDRA Code
10015688
MeSH ID
D005096
;
D015576
;
D005096
;
D054850
;
D005096
;
D036982
;
D005096
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Bone hypertrophy | Bone spur | Calcaneal spur | Exostosis | Exostosis of orbit | Exostosis of unspecified site | Foot exostosis | Hyperostosis | Hyperostosis of skull | Heel exostosis | Osteophytosis | Haglund deformity | Central osteophyte | Trochanteric osteophyte | Exostoses
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Not Available
Not Available
Not Available
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00036
Acitretin
-
-
BADD_D00066
Alendronic acid
0.007275%
BADD_D00086
Alprostadil
0.005262%
BADD_D00156
Apremilast
-
-
BADD_D00165
Aripiprazole
-
-
BADD_D00209
Baclofen
0.000505%
BADD_D00349
Capecitabine
-
-
BADD_D00410
Celecoxib
0.000230%
BADD_D00499
Clomipramine
-
-
BADD_D00500
Clomipramine hydrochloride
-
-
BADD_D00809
Escitalopram
-
-
BADD_D00898
Finasteride
0.000748%
BADD_D01103
Hydroxychloroquine
0.000405%
BADD_D01213
Isotretinoin
0.003789%
BADD_D01250
Lasofoxifene
-
-
BADD_D01252
Leflunomide
0.002066%
BADD_D01253
Lenalidomide
-
-
BADD_D01418
Methotrexate
0.001680%
BADD_D01431
Methylphenidate
0.000184%
BADD_D01567
Nilotinib
0.000533%
BADD_D01690
Pegaptanib
-
-
BADD_D01691
Pegaptanib sodium
-
-
BADD_D01835
Pregabalin
0.000354%
BADD_D01966
Ropinirole
-
-
BADD_D02026
Simvastatin
0.000031%
BADD_D02047
Sodium oxybate
0.004845%
BADD_D02236
Tofacitinib
0.011001%
BADD_D02254
Tramadol
-
-
BADD_D02346
Venlafaxine
-
-
BADD_D02369
Voriconazole
0.066556%
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