ADReCS

ADR Ontology

ADR Term

Chronic hepatitis

ADR ID

BADD_A00929

ADR Hierarchy

09 Hepatobiliary disorders

09.01 Hepatic and hepatobiliary disorders

09.01.07 Hepatocellular damage and hepatitis NEC

09.01.07.021 Chronic hepatitis

11 Infections and infestations

11.07 Ancillary infectious topics

11.07.01 Inflammatory disorders following infection

11.07.01.009 Chronic hepatitis

Description

INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors. | An aggressive form of chronic hepatitis involving extensive liver damage and cell injury beyond the portal tract. | A mild form of chronic hepatitis causing limited damage to the liver. [MeSH]

MedDRA Code

10008909

MeSH ID

D006521

ADR Severity Grade (FAERS)

ADR Severity Grade (CTCAE)

Not Available

Synonym

ADR Related Proteins

Protein Name	UniProt AC	TTD Target ID
Not Available	Not Available	Not Available

Drugs Leading to the ADR

Drug ID	Drug Name	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)
BADD_D00142	Anastrozole	0.002263%
BADD_D00174	Asfotase alfa	-	-
BADD_D00858	Everolimus	-	-
BADD_D00981	Gabapentin	0.000102%
BADD_D01242	Lamivudine	-	-
BADD_D01401	Metformin	0.000026%
BADD_D01405	Methadone	-	-
BADD_D01418	Methotrexate	-	-
BADD_D01470	Minocycline	0.002071%
BADD_D01496	Montelukast	0.000069%
BADD_D01668	Pantoprazole	0.000201%
BADD_D01817	Pramipexole	0.001459%
BADD_D01954	Rivaroxaban	0.000357%
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