Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Muscle tightness
ADR ID BADD_A04877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.007      Muscle tightness
Description The state of activity or tension of a muscle beyond that related to its physical properties, that is, its active resistance to stretch. In skeletal muscle, tonus is dependent upon efferent innervation. (Stedman, 25th ed) [MeSH]
MedDRA Code 10049816
MeSH ID D009129
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Neck tightness | Perioral tension | Tightness in jaw | Tightness of jaw muscles | Muscle tightness | Tightness of back muscles | Muscle tension | Muscle Tonus | Tonus, Muscle | Muscle Tightness | Tightness, Muscle | Muscular Tension | Tension, Muscular | Muscle Tension | Tension, Muscle
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01831Prednisolone0.000070%
BADD_D01835Pregabalin0.000456%
BADD_D01848Prochlorperazine--
BADD_D01888Quetiapine0.000174%
BADD_D01905Raltegravir0.003626%
BADD_D01922Regorafenib0.000112%
BADD_D01950Risedronic acid--
BADD_D01951Risperidone0.000655%
BADD_D01958Rizatriptan benzoate--
BADD_D01959Rocuronium0.000290%
BADD_D01961Rofecoxib--
BADD_D01966Ropinirole--
BADD_D01971Rosuvastatin0.000067%
BADD_D01982Salmeterol xinafoate--
BADD_D02007Semaxanib--
BADD_D02010Sertraline0.000136%
BADD_D02026Simvastatin0.000023%
BADD_D02029Sitagliptin--
BADD_D02038Sodium ferric gluconate complex-
BADD_D02047Sodium oxybate0.003138%
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02148Temazepam0.000120%
BADD_D02165Teriflunomide0.004171%
BADD_D02192Thalidomide0.000820%
BADD_D02236Tofacitinib0.010922%
BADD_D02259Trandolapril--
BADD_D02268Treprostinil0.000559%
BADD_D02281Trifluoperazine--
BADD_D02331Valsartan0.000053%
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