Drug Name |
Temazepam |
Drug ID |
BADD_D02148 |
Description |
Temazepam, like many other similar and related benzodiazepines, acts as a gamma-aminobutyric acid (GABA) modulator and is capable of eliciting a variety of actions including sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action [A175207, A175210, F3718, F3721].
Although the chemical synthesis of temazepam was established by 1965 [A175333], mainstream contemporary use of the medication did not occur until it's legitimate use as treatment for insomnia was accepted and approved later on. In particular, before temazepam saw regular prescription use in civilians it was - and still is - employed by the US military as a sedative-hypnotic medication to be taken by soldiers, pilots, etc. to obtain the necessary rest required for medical recovery or scheduled maneuvers and operations [A175339]. Regardless, temazepam has become one of the most frequently prescribed medications internationally and sees millions of prescriptions every year. Unfortunately, however, given its frequent use and the inherent nature of its pharmacological effects, temazepam - like many other benzodiazepines - possesses a high potential for misuse and is genuinely capable of developing drug tolerance, physical dependence, and addiction in users. |
Indications and Usage |
For the short-term treatment of insomnia (generally 7-10 days). |
Marketing Status |
Prescription; Discontinued |
ATC Code |
N05CD07 |
DrugBank ID |
DB00231
|
KEGG ID |
D00370
|
MeSH ID |
D013693
|
PubChem ID |
5391
|
TTD Drug ID |
D04BNP
|
NDC Product Code |
35356-821; 46708-380; 71610-625; 71335-1901; 71205-914; 63629-1054; 63629-1621; 17856-0148; 12828-0022; 65162-556; 61919-438; 46708-379; 53489-649; 63187-718; 55289-660; 70518-2926; 60429-507; 62332-381; 65162-557; 71610-101; 71335-0527; 43353-312; 60760-959; 70518-3093; 63629-8604; 67877-146; 70518-3057; 63187-132; 71610-626; 43547-613; 62332-382; 64330-088; 67877-149; 53489-651; 71335-0315; 55289-196; 67877-148; 63629-8603; 43547-611; 43353-260; 71610-004; 0406-9915; 71610-262; 0406-9960; 43547-612; 0904-6436; 63629-8605; 63629-8602; 62332-379; 68788-7163; 50090-0186; 68788-6986; 50090-0285; 62332-380; 0406-9917; 71610-089; 68084-549; 70518-3229; 65162-584; 70518-2487; 50090-3563; 0406-9962; 35356-664; 68071-2581; 53489-650; 0406-9916; 53489-648; 67544-136; 65162-583; 43353-152; 63629-1619; 46708-381; 0406-9961; 70518-3227; 61919-214; 71205-915; 46708-382; 65015-746; 0406-9914; 43547-614; 66267-321; 71335-2043; 48087-0045; 42291-797; 68788-8081; 63629-8601; 60429-506; 0228-2077; 0406-9959; 71610-086; 67877-147; 35356-663; 63629-8606; 68788-8139; 63187-497; 70518-2008; 0228-2076; 48087-0016; 63739-003; 61919-264; 63629-1057 |
Synonyms |
Temazepam | Hydroxydiazepam | Oxydiazepam | 3-Hydroxydiazepam | 3 Hydroxydiazepam | Methyloxazepam | Planum | PMS-Temazepam | PMS Temazepam | Pronervon T | Remestan | Restoril | Ro-5-5345 | Ro 5 5345 | Ro55345 | SaH 47-603 | SaH 47 603 | SaH 47603 | Signopam | Temaze | Temazep Von Ct | Von Ct, Temazep | Tenox | WY-3917 | WY 3917 | WY3917 | Apo-Temazepam | Apo Temazepam | Dasuen | Euhypnos | Gen-Temazepam | Gen Temazepam | Levanxol | Norkotral Tema | Tema, Norkotral | Normison | Temtabs | Nocturne | Normitab | Nortem | Novo-Temazepam | Novo Temazepam | Nu-Temazepam | Nu Temazepam |