Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Intestinal perforation
ADR ID BADD_A02389
ADR Hierarchy
07      Gastrointestinal disorders
07.04      Gastrointestinal ulceration and perforation
07.04.06      Intestinal ulcers and perforation NEC
07.04.06.002      Intestinal perforation
Description Opening or penetration through the wall of the INTESTINES. [MeSH]
MedDRA Code 10022694
MeSH ID D007416
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bowel perforation | Intestinal perforation | Intestinal perforation NOS | Peforation bowel | Perforated bowel | Perforation bowel | Perforation intestinal | Perforation of intestine | Intestinal Perforation | Intestinal Perforations | Perforation, Intestinal | Perforations, Intestinal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00535Crizotinib0.000336%
BADD_D00551Cyclosporine0.000111%
BADD_D00560Cytarabine0.000112%
BADD_D00563Dabigatran0.004037%
BADD_D00564Dabigatran etexilate--
BADD_D00566Dabrafenib0.000112%
BADD_D00594Deferasirox0.002478%
BADD_D00620Desoximetasone--
BADD_D00623Dexamethasone0.000291%
BADD_D00653Diclofenac0.000026%
BADD_D00680Dimethyl fumarate0.001800%
BADD_D00723Doxorubicin0.000168%
BADD_D00800Erlotinib--
BADD_D00854Etoposide0.000112%
BADD_D00858Everolimus0.000459%
BADD_D00879Fentanyl--
BADD_D00931Fluorouracil0.000276%
BADD_D00932Fluoxetine0.000020%
BADD_D00946Fluticasone furoate--
BADD_D00978Fulvestrant0.000334%
BADD_D01086Hydrocortisone--
BADD_D01119Ibrutinib0.000280%
BADD_D01120Ibuprofen0.000043%
BADD_D01130Idelalisib0.000168%
BADD_D01136Imatinib0.000224%
BADD_D01156Indomethacin0.000132%
BADD_D01196Irinotecan hydrochloride--
BADD_D01197Iron0.000453%
BADD_D01213Isotretinoin0.002316%
BADD_D01253Lenalidomide--
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