| ADR Ontology |
| ADR Term |
Guillain-Barre syndrome |
| ADR ID |
BADD_A01890 |
| ADR Hierarchy |
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| Description |
A disorder characterized by the body's immune system attacking the peripheral nervous system causing ascending paralysis. [CTCAE] An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314) [MeSH] |
| MedDRA Code |
10018767 |
| MeSH ID |
D020275; D020275; D020275
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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| Synonym |
| Acute infective polyneuritis | Guillain Barre syndrome | Guillain-Barre syndrome | Paralysis ascending | Syndrome Guillain-Barre | Acute inflammatory demyelinating polyradiculopathy | Acute inflammatory demyelinating polyradiculoneuropathy | Guillain-Barre Syndrome | Guillain Barre Syndrome | Syndrome, Guillain-Barre | Guillain-Barré Syndrome | Guillain Barré Syndrome | Guillain-Barré Syndromes | Syndrome, Guillain-Barré | Syndromes, Guillain-Barré | Acute Infectious Polyneuritis | Infectious Polyneuritis, Acute | Polyneuritis, Acute Infectious | Guillaine-Barre Syndrome | Guillaine Barre Syndrome | Syndrome, Guillaine-Barre | Acute Autoimmune Neuropathy | Acute Autoimmune Neuropathies | Autoimmune Neuropathies, Acute | Autoimmune Neuropathy, Acute | Neuropathies, Acute Autoimmune | Neuropathy, Acute Autoimmune | Landry-Guillain-Barre Syndrome | Landry Guillain Barre Syndrome | Syndrome, Landry-Guillain-Barre | Acute Inflammatory Demyelinating Polyneuropathy | Inflammatory Polyneuropathy Acute | Polyneuropathy Acute, Inflammatory | Acute Inflammatory Demyelinating Polyradiculoneuropathy | Acute Inflammatory Polyneuropathy | Acute Inflammatory Polyneuropathies | Inflammatory Polyneuropathies, Acute | Inflammatory Polyneuropathy, Acute | Polyneuropathies, Acute Inflammatory | Polyradiculoneuropathy, Acute Inflammatory | Acute Inflammatory Polyradiculoneuropathies | Inflammatory Polyradiculoneuropathies, Acute | Polyradiculoneuropathies, Acute Inflammatory | Polyneuropathy, Inflammatory Demyelinating, Acute | Demyelinating Polyradiculoneuropathy, Acute Inflammatory | Polyneuropathy, Acute Inflammatory | Polyradiculoneuropathy, Acute Inflammatory Demyelinating | Inflammatory Demyelinating Polyradiculoneuropathy, Acute | Acute Inflammatory Polyradiculoneuropathy | Guillain-Barre Syndrome, Familial | Familial Guillain-Barre Syndrome | Familial Guillain-Barre Syndromes | Guillain Barre Syndrome, Familial | Guillain-Barre Syndromes, Familial | Syndrome, Familial Guillain-Barre | Syndromes, Familial Guillain-Barre |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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