Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02249Topotecan hydrochloride--
BADD_D02250Toremifene citrate0.000734%
BADD_D02251Torsemide0.001001%
BADD_D02253Trabectedin0.001366%
BADD_D02254Tramadol--
BADD_D02255Tramadol hydrochloride--
BADD_D02256Tramazoline--
BADD_D02257Trametinib0.007589%
BADD_D02258Trametinib dimethyl sulfoxide--
BADD_D02259Trandolapril--
BADD_D02260Trandolaprilat--
BADD_D02261Tranexamic acid--
BADD_D02262Tranylcypromine0.009425%
BADD_D02264Trastuzumab--
BADD_D02265Travoprost--
BADD_D02266Trazodone--
BADD_D02267Trazodone hydrochloride--
BADD_D02268Treprostinil0.022042%
BADD_D02269Treprostinil sodium--
BADD_D02270Tretinoin--
BADD_D02271Triamcinolone--
BADD_D02272Triamcinolone acetonide--
BADD_D02275Triamterene--
BADD_D02276Triamterene hydrochlorothiazide--
BADD_D02277Triazolam--
BADD_D02281Trifluoperazine--
BADD_D02282Trifluoperazine hydrochloride--
BADD_D02287Trimethadione--
BADD_D02292Trimetrexate--
BADD_D02293Trimetrexate glucuronate--
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ADReCS-Target
ADR Term Drug Name Target