Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Torsemide
Drug ID BADD_D02251
Description Torasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.[A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257]
Indications and Usage For the treatment of edema associated with congestive heart failure, renal disease, or hepatic disease. Also for the treatment of hypertension alone or in combination with other antihypertensive agents.
Marketing Status Prescription; Discontinued
ATC Code C03CA04
DrugBank ID DB00214
KEGG ID D00382
MeSH ID D000077786
PubChem ID 41781
TTD Drug ID D0J9XZ
NDC Product Code 50268-755; 65862-126; 65862-127; 43353-315; 51604-0020; 42291-817; 57237-140; 73502-286; 72189-102; 50268-757; 57237-141; 50268-754; 63629-1346; 70518-2744; 68554-0025; 65862-125; 0517-0771; 42291-819; 51407-362; 65862-128; 68084-539; 31722-531; 73502-288; 73502-586; 64220-125; 31722-530; 42291-818; 31722-529; 57237-138; 57451-1189; 57237-139; 50268-756; 0517-0770; 66064-1012; 50111-915; 31722-532; 71052-688; 42291-816; 0054-0077; 50111-918; 71335-0297; 0615-7997; 73502-687; 69037-0054; 65862-539; 70518-2195; 50111-917; 73502-287; 51604-0018; 72166-010; 72969-073; 73502-786; 50111-916
Synonyms Torsemide | Torasemide | 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea | 1-Isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea | Demadex
Chemical Information
Molecular Formula C16H20N4O3S
CAS Registry Number 56211-40-6
SMILES CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alkalosis hypochloraemic14.01.02.003--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Blood uric acid increased13.02.04.001--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
Dehydration14.05.05.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspepsia07.01.02.001--
Electrocardiogram abnormal13.14.05.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gout15.01.06.001; 14.09.01.001--Not Available
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperuricaemia14.09.01.003--
Hypokalaemia14.05.03.002--
Hyponatraemia14.05.04.002--
Hypotension24.06.03.002--
Hypovolaemia14.05.05.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Leukopenia01.02.02.001--Not Available
Loss of consciousness17.02.04.004--Not Available
The 1th Page    1 2    Next   Last    Total 2 Pages