Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01546Nefazodone--
BADD_D01547Nefazodone hydrochloride--
BADD_D01555Nepafenac0.002941%
BADD_D01564Nicotine0.001379%
BADD_D01567Nilotinib0.002350%
BADD_D01592Obeticholic acid0.012405%
BADD_D01594Ocriplasmin--
BADD_D01598Ofloxacin--
BADD_D01599Olanzapine0.001242%
BADD_D01600Olanzapine pamoate--
BADD_D01605Olopatadine0.000637%
BADD_D01606Olopatadine hydrochloride--
BADD_D01607Olsalazine--
BADD_D01608Olsalazine sodium--
BADD_D01609Omacetaxine mepesuccinate--
BADD_D01614Omeprazole--
BADD_D01615Omeprazole magnesium--
BADD_D01616Onabotulinumtoxina--
BADD_D01617Ondansetron0.000021%
BADD_D01643Oxybutynin--
BADD_D01653Paclitaxel--
BADD_D01654Palbociclib0.012872%
BADD_D01656Paliperidone--
BADD_D01668Pantoprazole0.000041%
BADD_D01679Paroxetine--
BADD_D01690Pegaptanib--
BADD_D01703Pemirolast--
BADD_D01704Pemirolast potassium--
BADD_D01730Pentostatin--
BADD_D01771Pilocarpine hydrochloride0.005051%
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