Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pemirolast
Drug ID BADD_D01703
Description Pemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis. Pemirolast is potentially useful for prophylaxis of pulmonary hypersensitivity reactions to drugs such as paclitaxel.
Indications and Usage For the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis
Marketing Status Discontinued
ATC Code Not Available
DrugBank ID DB00885
KEGG ID D07476
MeSH ID C055139
PubChem ID 57697
TTD Drug ID D0K5LQ
NDC Product Code Not Available
Synonyms pemirolast | 9-methyl-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one | pemirolast potassium salt | BMY 26517 | BMY-26517 | 9-TBX | Alamast
Chemical Information
Molecular Formula C10H8N6O
CAS Registry Number 69372-19-6
SMILES CC1=CC=CN2C1=NC=C(C2=O)C3=NNN=N3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Back pain15.03.04.005--
Body temperature increased13.15.01.001--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Cough22.02.03.001--
Dry eye06.08.02.001--
Dysmenorrhoea21.01.01.002--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Influenza22.07.02.001; 11.05.03.001--Not Available
Nasal congestion22.04.04.001--
Rhinitis22.07.03.006; 11.01.13.004--
Sinusitis11.01.13.005; 22.07.03.007--
Sneezing22.02.05.011--
Ocular discomfort06.08.03.008--Not Available
Sensation of foreign body08.01.09.002--Not Available
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