Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01933Ribavirin--
BADD_D01937Rifapentine--
BADD_D01938Rifaximin0.005176%
BADD_D01942Riluzole--
BADD_D01943Rimabotulinumtoxinb--
BADD_D01944Rimantadine--
BADD_D01945Rimantadine hydrochloride--
BADD_D01948Riociguat0.004681%
BADD_D01949Risedronate sodium--
BADD_D01950Risedronic acid--
BADD_D01951Risperidone--
BADD_D01952Ritonavir--
BADD_D01954Rivaroxaban--
BADD_D01955Rivastigmine--
BADD_D01956Rivastigmine tartrate--
BADD_D01957Rizatriptan--
BADD_D01961Rofecoxib--
BADD_D01962Roflumilast--
BADD_D01963Rolapitant0.000081%
BADD_D01964Romidepsin--
BADD_D01966Ropinirole--
BADD_D01967Ropinirole hydrochloride--
BADD_D01968Ropivacaine hydrochloride--
BADD_D01970Rosiglitazone maleate--
BADD_D01971Rosuvastatin--
BADD_D01972Rosuvastatin calcium--
BADD_D01973Rotigotine0.001834%
BADD_D01974Rotigotine hydrochloride--
BADD_D01977Rufinamide--
BADD_D01978Ruxolitinib0.011349%
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