Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Risedronate sodium
Drug ID BADD_D01949
Description Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage For the treatment of Paget's disease of the bone (osteitis deformans), postmenopausal and glucocorticoid-induced osteoporosis
Marketing Status Prescription; Discontinued
ATC Code M05BA07
DrugBank ID DB00884
KEGG ID D00942
MeSH ID D000068296
PubChem ID 4194514
TTD Drug ID D0PA5S
NDC Product Code 65862-517; 0430-0979; 65977-0092; 33342-109; 60723-041; 70771-1436; 47335-667; 65372-1113; 16714-870; 47335-928; 63304-440; 59762-0407; 0093-3098; 0093-3100; 33342-107; 53104-7653; 65862-518; 0430-0478; 59762-0405; 14998-0008; 65096-0110; 0430-0473; 59762-0406; 65862-519; 47335-666; 47335-668; 11722-077; 65862-870; 0430-0472; 0430-0970; 68382-075; 80426-042; 47335-727; 0093-3099; 60505-3165; 60505-3097; 0430-0487; 62331-017; 33342-108; 60505-3096; 0093-7771
Synonyms Risedronic Acid | 1-Hydroxy-2-(3-pyridyl)ethylidene diphosphonate | Atelvia | Risedronate Sodium | 2-(3-pyridinyl)-1-hydroxyethylidene-bisphosphonate | 2-(3-pyridinyl)-1-hydroxyethylidenebisphosphonate | Risedronic Acid, Monosodium Salt | Actonel | Risedronate | Bisphosphonate Risedronate Sodium | Risedronate Sodium, Bisphosphonate | Sodium, Bisphosphonate Risedronate
Chemical Information
Molecular Formula C7H10NNaO7P2
CAS Registry Number 115436-72-1
SMILES C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)[O-].[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Arthralgia15.01.02.001--
Back pain15.03.04.005--
Bone pain15.02.01.001--
Bronchitis11.01.09.001; 22.07.01.001--
Constipation07.02.02.001--
Dermatitis bullous23.03.01.002--
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspepsia07.01.02.001--
Gastric ulcer07.04.03.002--
Headache17.14.01.001--
Influenza22.07.02.001; 11.05.03.001--Not Available
Iritis10.02.01.022; 06.04.03.002--Not Available
Muscle spasms15.05.03.004--
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Oesophageal ulcer07.04.05.002--
Oesophagitis07.08.05.001--
Pain in extremity15.03.04.010--
Rash generalised23.03.13.002--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Uveitis06.04.03.003; 10.02.01.023--
Vomiting07.01.07.003--
Osteonecrosis of jaw24.04.05.005; 15.02.04.010--
Gastrointestinal tract irritation07.08.03.008--Not Available
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