| Drug Name |
Ropinirole hydrochloride |
| Drug ID |
BADD_D01967 |
| Description |
Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547]. It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547].
In 2008, the extended-release capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and offering a similar side effect profile and efficacy to previous formulations of ropinirole [A35711]. |
| Indications and Usage |
For the treatment of the signs and symptoms of Parkinson's disease and for the treatment of primary moderate-severe restless legs syndrome [FDA label]. |
| Marketing Status |
approved; investigational |
| ATC Code |
N04BC04 |
| DrugBank ID |
DB00268
|
| KEGG ID |
D00784
|
| MeSH ID |
C046649
|
| PubChem ID |
68727
|
| TTD Drug ID |
D0R9EQ
|
| NDC Product Code |
43547-269; 43547-270; 43547-599; 65841-716; 70518-2476; 54752-0005; 43547-597; 43547-598; 46708-033; 50090-4348; 62332-036; 63629-4641; 0615-8188; 0904-6373; 43547-596; 46708-031; 46708-032; 50268-743; 55154-7633; 55154-7888; 61919-564; 65841-714; 71335-1626; 0615-8190; 65841-718; 65096-0102; 43547-271; 62332-033; 62332-034; 65841-715; 71335-1434; 0615-8189; 62147-0015; 43547-595; 46708-030; 46708-035; 62332-035; 61187-008; 62147-0008; 64220-121; 43547-273; 50090-1330; 60687-588; 62332-030; 63629-4798; 71335-0727; 0904-6374; 43547-272; 46708-036; 62332-032; 71335-0587; 71335-0829; 0615-8191; 43547-274; 43547-600; 50268-742; 50268-744; 62332-031; 55111-091; 46708-034; 60687-577; 65841-712; 65841-713; 65841-717; 58032-0133; 66039-853; 43547-268; 43547-601; 50268-741 |
| UNII |
D7ZD41RZI9
|
| Synonyms |
ropinirole | 4-(2-(di-n-propylamino)ethyl)-2(3H)-indolone | ropinirol | SK&F 101468 | SKF 101468 | SK&F-101,468 | Requip | ropinirole hydrochloride |
