Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Alveolar proteinosis
ADR ID BADD_A00156
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.01      Lower respiratory tract disorders (excl obstruction and infection)
22.01.02      Parenchymal lung disorders NEC
22.01.02.009      Alveolar proteinosis
Description A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR. [MeSH]
MedDRA Code 10001881
MeSH ID D011649
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Alveolar proteinosis | Pulmonary alveolar proteinosis | Pulmonary Alveolar Proteinosis | Alveolar Proteinosis, Pulmonary | Proteinosis, Pulmonary Alveolar | Pulmonary Alveolar Proteinoses | Alveolar Proteinoses, Pulmonary | Proteinoses, Pulmonary Alveolar
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00194Azacitidine0.000208%
BADD_D00551Cyclosporine0.000203%
BADD_D00589Dasatinib0.000208%
BADD_D00594Deferasirox0.005831%
BADD_D00858Everolimus--
BADD_D00879Fentanyl0.000252%
BADD_D01507Mycophenolate mofetil0.001194%
BADD_D02028Sirolimus--
BADD_D02105Tacrolimus0.002037%
BADD_D02214Ticagrelor0.001149%
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