Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Activated partial thromboplastin time prolonged
ADR ID BADD_A00069
ADR Hierarchy
13      Investigations
13.01      Haematology investigations (incl blood groups)
13.01.02      Coagulation and bleeding analyses
13.01.02.001      Activated partial thromboplastin time prolonged
Description A finding based on laboratory test results in which the partial thromboplastin time is found to be greater than the control value. As a possible indicator of coagulopathy, a prolonged partial thromboplastin time (PTT) may occur in a variety of diseases and disorders, both primary and related to treatment. [CTCAE]
MedDRA Code 10000636
MeSH ID Not Available
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Activated partial thromboplastin time increased | Activated partial thromboplastin time prolonged | APTT increased | APTT prolonged | Kaolin cephalin clotting time prolonged | KCCT increased | Partial thromboplastin time prolonged | PTT prolonged
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00175Asparaginase--
BADD_D00206Aztreonam--
BADD_D00376Caspofungin--
BADD_D00386Cefepime--
BADD_D00387Cefepime hydrochloride--
BADD_D00395Cefpodoxime--
BADD_D00396Cefpodoxime proxetil--
BADD_D00410Celecoxib--
BADD_D00602Delamanid--
BADD_D00603Delavirdine--
BADD_D00702Dolasetron--
BADD_D00858Everolimus--
BADD_D00870Febuxostat--
BADD_D00957Fondaparinux sodium--
BADD_D01058Hemin--
BADD_D01261Leuprolide monoacetate--
BADD_D01501Moxifloxacin--
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01507Mycophenolate mofetil--
BADD_D01729Pentosan polysulfate sodium--
BADD_D01779Piperacillin--
BADD_D02031Sitaxentan--
BADD_D02105Tacrolimus--
BADD_D02170Testosterone--
BADD_D02205Thrombin (human)--
BADD_D02217Tigecycline--
BADD_D02343Velaglucerase alfa--
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