Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Hemin
Drug ID BADD_D01058
Description Hemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.
Indications and Usage Used in the management of porphyria attacks, particularly in acute intermittent porphyria.
Marketing Status Not Available
ATC Code B06AB01
DrugBank ID DB03404
KEGG ID D10003
MeSH ID D006427
PubChem ID 26945
TTD Drug ID D0UU1I
NDC Product Code 51014-7945; 55292-702
Synonyms Hemin | Ferriheme Chloride | Chloride, Ferriheme | Protohemin IX | Protohemin | Chlorohemin | Ferriprotoporphyrin IX Chloride | Chloride, Ferriprotoporphyrin IX | Ferrihaem | Panhematin | Ferriprotoporphyrin IX | Hematin | Alkaline Hematin D-575 | Alkaline Hematin D 575 | Hematin D-575, Alkaline | Ferriprotoporphyrin
Chemical Information
Molecular Formula C34H32FeN4O4
CAS Registry Number 14875-96-8
SMILES CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C) CCC(=O)O)CCC(=O)O.[Fe+2]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Activated partial thromboplastin time prolonged13.01.02.001--
Body temperature increased13.15.01.001--Not Available
Coagulopathy01.01.02.001--Not Available
Leukocytosis01.02.01.002--
Phlebitis24.05.03.001; 12.02.01.002--
Prothrombin level increased13.01.02.011--Not Available
Pyrexia08.05.02.003--
Serum ferritin increased13.11.01.026--Not Available
Thrombocytopenia01.08.01.002--Not Available
Iron overload14.13.03.002; 12.02.08.005--
Acute kidney injury20.01.03.016--
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