Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Velaglucerase alfa
Drug ID BADD_D02343
Description Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Indications and Usage Velaglucerase alfa is a hydrolytic lysosomal glucocerebroside-specific enzyme indicated for long-term enzyme replacement therapy for pediatric and adult patients with type 1 Gaucher disease.
Marketing Status Not Available
ATC Code A16AB10
DrugBank ID DB06720
KEGG ID D09029
MeSH ID Not Available
PubChem ID Not Available
TTD Drug ID D0G5ET
NDC Product Code 54092-701
Synonyms Not Available
Chemical Information
Molecular Formula Not Available
CAS Registry Number 884604-91-5
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Activated partial thromboplastin time prolonged13.01.02.001--
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Bone pain15.02.01.001--
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.003--
Fatigue08.01.01.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Headache17.14.01.001--
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Nausea07.01.07.001--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Tachycardia02.03.02.007--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urticaria10.01.06.001; 23.04.02.001--
Infusion related reaction12.02.05.009; 10.01.01.017; 08.01.03.002--
Antibody test13.06.03.009--Not Available
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