Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ganciclovir sodium
Drug ID BADD_D01004
Description An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Indications and Usage For induction and maintenance in the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). Also used in the treatment of severe cytomegalovirus (CMV) disease, including CMV pneumonia, CMV gastrointestinal disease, and disseminated CMV infections, in immunocompromised patients.
Marketing Status Prescription; Discontinued
ATC Code J05AB06; S01AD09
DrugBank ID DB01004
KEGG ID D04301
MeSH ID D015774
PubChem ID 23700083
TTD Drug ID D05ARP
NDC Product Code 51817-171; 25021-185; 63323-315; 0004-6941; 61269-450; 0143-9299; 70436-089; 46014-1054
Synonyms Ganciclovir | Gancyclovir | BW-759 | Ganciclovir Sodium | Ganciclovir, Monosodium Salt | RS-21592 | BIOLF-62 | Cytovene
Chemical Information
Molecular Formula C9H12N5NaO4
CAS Registry Number 84245-13-6
SMILES C1=NC2=C(N1COC(CO)CO)N=C(N=C2[O-])N.[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Flatulence07.01.04.002--
Gastrointestinal perforation07.04.04.001--Not Available
Granulocytopenia01.02.03.003--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Haemolytic anaemia01.06.03.002--Not Available
Haemolytic uraemic syndrome20.01.03.011; 01.06.02.001--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatic function abnormal09.01.02.001--Not Available
Hepatitis09.01.07.004--Not Available
Hypercalcaemia14.04.01.003; 05.04.01.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023--Not Available
Hyponatraemia14.05.04.002--
Hypotension24.06.03.002--
IIIrd nerve paralysis17.04.02.003; 06.05.02.011--Not Available
Infection11.01.08.002--Not Available
Infertility21.03.02.001--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Injection site inflammation12.07.03.009; 08.02.03.008--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Intestinal ulcer07.04.06.003--Not Available
Intracranial pressure increased17.07.02.002--Not Available
Irritability19.04.02.013; 08.01.03.011--
Leukopenia01.02.02.001--Not Available
Macular oedema06.04.06.005--Not Available
Malaise08.01.01.003--
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