Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fluphenazine
Drug ID BADD_D00935
Description A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Indications and Usage For management of manifestations of psychotic disorders.
Marketing Status approved
ATC Code N05AB02
DrugBank ID DB00623
KEGG ID D07977
MeSH ID D005476
PubChem ID 3372
TTD Drug ID D0P5SA
NDC Product Code Not Available
UNII S79426A41Z
Synonyms Fluphenazine | Flufenazin | Fluphenazine Hydrochloride | Hydrochloride, Fluphenazine | Lyogen | Prolixin
Chemical Information
Molecular Formula C22H26F3N3OS
CAS Registry Number 69-23-8
SMILES C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Glaucoma06.03.01.002--
Gynaecomastia21.05.04.003; 05.05.02.003--
Headache17.14.01.001--
Hepatocellular injury09.01.07.008--Not Available
Hyperkinesia17.01.02.008--Not Available
Hyperreflexia17.02.01.002--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hypokinesia17.01.02.009--Not Available
Hypotension24.06.03.002--
Hypotonia17.05.02.002; 15.05.04.008--Not Available
Ileus paralytic07.02.05.001--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Irritability19.04.02.013; 08.01.03.011--
Jaundice cholestatic09.01.01.005--Not Available
Laryngeal oedema23.04.01.005; 22.04.02.001; 10.01.05.003--
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Leukocytosis01.02.01.002--
Leukopenia01.02.02.001--Not Available
Libido increased21.03.02.007; 19.08.03.002--
Menstruation irregular21.01.01.005; 05.05.01.008--
Mitral valve incompetence02.07.01.002--Not Available
Muscle rigidity17.05.02.005; 15.05.04.001--Not Available
Muscle spasms15.05.03.004--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Neurogenic bladder20.03.03.001; 17.10.01.002--Not Available
Neuroleptic malignant syndrome08.05.01.005; 17.05.02.003; 15.05.04.015; 12.03.01.003--Not Available
Oculogyric crisis17.01.03.002; 06.05.02.002--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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