| Drug Name |
Dexamethasone phosphate |
| Drug ID |
BADD_D00624 |
| Description |
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions.[L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and [prednisolone].[A188724]
Dexamethasone was granted FDA approval on 30 October 1958.[L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms. Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one fifth in those requiring oxygen.[L14318] |
| Indications and Usage |
Intranasal aerosol: for the treatment of allergic ot inflammatory nasal conditions, and nasal polyps |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
A01AC02; C05AA09; D07AB19; D07XB05; D10AA03; H02AB02; R01AD03; S01BA01; S01CB01; S02BA06; S03BA01 |
| DrugBank ID |
DB01234
|
| KEGG ID |
D07802
|
| MeSH ID |
C004180
|
| PubChem ID |
9400
|
| TTD Drug ID |
D0NA8U
|
| NDC Product Code |
0009-5019; 55718-157; 42195-270; 47781-914; 47781-916; 55700-961; 63629-4127; 63629-7850; 67296-0326; 68071-4127; 0054-8183; 46439-8765; 51552-0430; 55718-133; 48102-050; 48102-051; 51407-361; 61919-827; 68788-7142; 70518-2998; 0054-4184; 0054-4186; 49452-2465; 57582-031; 65089-0045; 42195-127; 55289-903; 60219-2043; 60219-2044; 63187-561; 64980-509; 69306-111; 69306-114; 0054-4181; 0054-8175; 71161-138; 79572-012; 82298-111; 43063-266; 63629-3742; 63629-4129; 68071-2321; 68788-7267; 0054-4182; 0054-8176; 52128-170; 50090-0089; 50090-0090; 50090-0091; 63629-7806; 69306-112; 71205-012; 0054-4180; 0054-8174; 51927-1081; 0998-0615; 42195-490; 45865-989; 48102-052; 49999-059; 0023-3348; 55289-582; 55700-854; 0054-4179; 72189-254; 72893-015; 0395-8142; 22552-0039; 55718-156; 42195-721; 48102-047; 48102-049; 61919-269; 70382-204; 0054-3177; 71205-013; 0054-8179; 79043-200; 0121-0907; 55154-4914; 0054-8181; 71879-001; 60722-3013; 15014-211; 42195-121; 42195-151; 60432-466; 63187-383; 67296-1413; 70518-1534; 0054-4183; 0054-8180; 38779-0405; 0121-1814; 42195-149; 42195-221; 50090-0088; 54879-003; 55154-4901; 70518-3050 |
| Synonyms |
dexamethasone 21-phosphate | dexamethasone phosphate | dexamethasone 21-phosphate, monosodium salt, (11beta,16alpha)-isomer | dexamethasone sodium phosphate | dexamethasonedisodium phosphate | dexamethasone phosphate disodium salt | Solu- Decadron | Spersadex | Spersadox | dexamethasone 21-phosphate, (6alpha,11beta,16alpha)-isomer | dexamethasone 21-phosphate, disodium salt, (11beta,16alpha)-isomer | dexamethasone 21-phosphate, disodium salt, (6alpha,11beta,16alpha)-isomer | Decadron phosphate | dexamethasone 21-phosphate, sodium salt, (11beta,16alpha)-isomer | dexamethasone 21-phosphate, copper (+2) salt (2:3), (11beta,16alpha)-isomer |
