Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefpodoxime
Drug ID BADD_D00395
Description Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
Indications and Usage For the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms.
Marketing Status Not Available
ATC Code J01DD13
DrugBank ID DB01416
KEGG ID D07650
MeSH ID C053268
PubChem ID 6335986
TTD Drug ID D0W6CA
NDC Product Code Not Available
Synonyms cefpodoxime | U 76253A | U-76,253A | RU 51746 | RU-51746 | R 3746 | R-3746 | R 3763 | R-3763
Chemical Information
Molecular Formula C15H17N5O6S2
CAS Registry Number 80210-62-4
SMILES COCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Proteinuria20.02.01.011--
Prothrombin level increased13.01.02.011--Not Available
Pruritus23.03.12.001--
Pseudomembranous colitis11.02.02.002; 07.19.01.003--Not Available
Rash23.03.13.001--Not Available
Rash maculo-papular23.03.13.004--
Rash pustular23.03.10.003; 11.01.12.002--
Rectal haemorrhage24.07.02.018; 07.12.03.001--
Renal failure20.01.03.005--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Seizure17.12.03.001--
Serum sickness12.02.08.004; 10.01.03.004--
Serum sickness-like reaction10.01.03.005; 08.01.03.003--Not Available
Shock24.06.02.002--Not Available
Sinusitis22.07.03.007; 11.01.13.005--
Skin exfoliation23.03.07.003--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.03.020--
Stomatitis07.05.06.005--
Sunburn12.05.02.001; 23.03.09.007--Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tension19.06.02.005--Not Available
Thirst14.03.02.007; 08.01.09.021--Not Available
Thrombocytopenia01.08.01.002--Not Available
Thrombocytopenic purpura23.06.01.007; 01.08.01.003--Not Available
Thrombocytosis01.08.02.001--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tongue disorder07.14.01.002--Not Available
Tooth disorder07.09.05.001--Not Available
Toothache07.09.06.001--
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