Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Aminocaproic acid
Drug ID BADD_D00106
Description An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Indications and Usage For use in the treatment of excessive postoperative bleeding.
Marketing Status Prescription; Discontinued
ATC Code B02AA01
DrugBank ID DB00513
KEGG ID D00160
MeSH ID D015119
PubChem ID 564
TTD Drug ID D0FD0H
NDC Product Code 52584-346; 71151-026; 42799-054; 72572-015; 69766-054; 52817-815; 0517-9191; 71052-265; 17478-769; 0517-9120; 0404-9812; 69315-232; 0904-7165; 66689-330; 46438-0641; 59285-019; 60219-1637; 69315-503; 69680-115; 17478-768; 60687-505; 69315-231; 49411-052; 72205-049; 69680-116; 69539-161; 76055-0030; 69238-1596; 70966-0010; 49411-050; 69238-1637; 47621-310; 49411-051; 62559-225; 0409-4346; 51927-0046; 17478-447; 65571-0025
Synonyms Aminocaproic Acid | 6-Aminohexanoic Acid | 6 Aminohexanoic Acid | epsilon-Aminocaproic Acid | epsilon Aminocaproic Acid | 6-Aminocaproic Acid | 6 Aminocaproic Acid | Capralense | Capramol | Caproamin | Caprocid | Hexalense | CY-116 | CY 116 | CY116 | Epsamon | Epsikapron | Hemocaprol | Amicar | Caprolest
Chemical Information
Molecular Formula C6H13NO2
CAS Registry Number 60-32-2
SMILES C(CCC(=O)O)CCN
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypersensitivity10.01.03.003--
Hypotension24.06.03.0020.002723%
Hypoxia22.02.02.0030.001089%
Injection site reaction12.07.03.015; 08.02.03.014--
Intracranial pressure increased17.07.02.002--Not Available
Lacrimation increased06.08.02.004--
Leukopenia01.02.02.001--Not Available
Liver function test abnormal13.03.01.013--Not Available
Local reaction08.01.03.012--Not Available
Loss of consciousness17.02.04.0040.001089%Not Available
Malaise08.01.01.003--
Muscular weakness17.05.03.005; 15.05.06.001--
Myalgia15.05.02.001--
Myopathy15.05.05.001--Not Available
Myositis15.05.01.001--
Nasal congestion22.04.04.001--
Nausea07.01.07.0010.001634%
Necrosis24.04.02.006; 08.03.03.001--Not Available
Nervousness19.06.02.0030.001089%Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Pain08.01.08.004--
Peripheral ischaemia24.04.03.002--
Pruritus23.03.12.001--
Pulmonary embolism24.01.06.001; 22.06.02.0010.001089%Not Available
Pyrexia08.05.02.0030.001089%
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Respiratory failure22.02.06.002; 14.01.04.0030.000284%
Rhabdomyolysis15.05.05.002--
Seizure17.12.03.0010.001089%
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