Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Vasogenic cerebral oedema
ADR ID BADD_A08895
ADR Hierarchy
17      Nervous system disorders
17.07      Increased intracranial pressure and hydrocephalus
17.07.02      Increased intracranial pressure disorders
17.07.02.008      Vasogenic cerebral oedema
Description Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6) [MeSH]
MedDRA Code 10067275
MeSH ID D001929
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Vasogenic cerebral oedema | Vasogenic cerebral edema | Brain Edema | Edema, Brain | Intracranial Edema | Edema, Intracranial | Brain Swelling | Brain Swellings | Swelling, Brain | Vasogenic Cerebral Edema | Cerebral Edemas, Vasogenic | Edema, Vasogenic Cerebral | Cerebral Edema, Vasogenic | Cytotoxic Cerebral Edema | Cerebral Edema, Cytotoxic | Edema, Cytotoxic Cerebral | Vasogenic Brain Edema | Brain Edema, Vasogenic | Edema, Vasogenic Brain | Cerebral Edema | Edema, Cerebral | Cytotoxic Brain Edema | Brain Edema, Cytotoxic | Edema, Cytotoxic Brain
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000265%
BADD_D00167Armodafinil0.002281%
BADD_D00504Clopidogrel0.000098%
BADD_D01258Leucovorin0.005831%
BADD_D01765Phenytoin0.001639%
BADD_D01834Prednisone0.000040%
BADD_D02150Temozolomide0.000533%
BADD_D02373Warfarin0.000300%
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