Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Heart injury
ADR ID BADD_A08521
ADR Hierarchy
02      Cardiac disorders
02.01      Cardiac disorder signs and symptoms
02.01.01      Cardiac disorders NEC
02.01.01.010      Heart injury
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.11      Cardiovascular injuries
12.01.11.003      Heart injury
Description General or unspecified injuries to the heart. [MeSH]
MedDRA Code 10061200
MeSH ID D006335
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Heart injury NOS | Heart injury, with open wound into thorax | Heart injury, without mention of open wound into thorax | Injury to heart and lung | Injury to heart, with open wound into thorax | Injury to heart, without open wound into thorax | Laceration of heart with penetration of heart chambers and open wound into thorax | Laceration of heart with penetration of heart chambers, without mention of open wound into thorax | Laceration of heart without penetration of heart chambers or open wound into thorax | Laceration of heart without penetration of heart chambers, with open wound into thorax | Unspecified injury of heart with open wound into thorax | Unspecified injury of heart without mention of open wound into thorax | Heart injury | Penetrating cardiac trauma | Heart Injuries | Injuries, Heart | Heart Injury | Injury, Heart | Heart Rupture, Traumatic | Heart Ruptures, Traumatic | Rupture, Traumatic Heart | Ruptures, Traumatic Heart | Traumatic Heart Rupture | Traumatic Heart Ruptures | Cardiac Rupture, Traumatic | Cardiac Ruptures, Traumatic | Rupture, Traumatic Cardiac | Ruptures, Traumatic Cardiac | Traumatic Cardiac Rupture | Traumatic Cardiac Ruptures
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam0.000044%
BADD_D00312Bupropion0.000088%
BADD_D00511Clozapine--
BADD_D00564Dabigatran etexilate--
BADD_D00668Digoxin0.000636%
BADD_D00720Doxepin0.001036%
BADD_D00723Doxorubicin0.000533%
BADD_D00794Ergocalciferol0.000152%
BADD_D00879Fentanyl0.001010%
BADD_D00981Gabapentin0.000102%
BADD_D01401Metformin0.000065%
BADD_D01431Methylphenidate0.000275%
BADD_D01498Morphine0.000469%
BADD_D01777Pioglitazone0.000384%
BADD_D01864Propofol0.001182%
BADD_D01951Risperidone0.001341%
BADD_D02170Testosterone0.002478%
BADD_D02419Rosiglitazone0.014017%
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