Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Plasma cell myelomas
ADR ID BADD_A06747
ADR Hierarchy
01      Blood and lymphatic system disorders
01.14      Plasma cell neoplasms
01.14.02      Plasma cell myelomas
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.23      Plasma cell neoplasms
16.23.02      Plasma cell myelomas
Description A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. [MeSH]
MedDRA Code 10074470
MeSH ID D009101
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Multiple Myeloma | Multiple Myelomas | Myelomas, Multiple | Myeloma, Multiple | Myeloma, Plasma-Cell | Myeloma, Plasma Cell | Myelomas, Plasma-Cell | Plasma-Cell Myeloma | Plasma-Cell Myelomas | Myelomatosis | Myelomatoses | Plasma Cell Myeloma | Cell Myeloma, Plasma | Cell Myelomas, Plasma | Myelomas, Plasma Cell | Plasma Cell Myelomas | Kahler Disease | Disease, Kahler | Myeloma-Multiple | Myeloma Multiple | Myeloma-Multiples
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug Name
BADD_D00066Alendronic acid
BADD_D00076Allopurinol
BADD_D00151Apixaban
BADD_D00156Apremilast
BADD_D00194Azacitidine
BADD_D00271Bicalutamide
BADD_D00284Bortezomib
BADD_D00356Carbamazepine
BADD_D00364Carboplatin
BADD_D00367Carfilzomib
BADD_D00497Clomiphene
BADD_D00498Clomiphene citrate
BADD_D00511Clozapine
BADD_D00551Cyclosporine
BADD_D00564Dabigatran etexilate
BADD_D00589Dasatinib
BADD_D00594Deferasirox
BADD_D00623Dexamethasone
BADD_D00680Dimethyl fumarate
BADD_D00723Doxorubicin
BADD_D00732Droxidopa
BADD_D00759Eltrombopag
BADD_D00774Entecavir
BADD_D00794Ergocalciferol
BADD_D00858Everolimus
BADD_D00952Folic acid
BADD_D00981Gabapentin
BADD_D01038Goserelin
BADD_D01110Hydroxyurea
BADD_D01136Imatinib
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