Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Gestational hypertension
ADR ID BADD_A06614
ADR Hierarchy
18      Pregnancy, puerperium and perinatal conditions
18.02      Maternal complications of pregnancy
18.02.03      Hypertension associated disorders of pregnancy
18.02.03.004      Gestational hypertension
24      Vascular disorders
24.08      Vascular hypertensive disorders
24.08.07      Pregnancy associated hypertension
24.08.07.004      Gestational hypertension
Description A condition in pregnant women with elevated systolic (>140 mm Hg) and diastolic (>90 mm Hg) blood pressure on at least two occasions 6 h apart. HYPERTENSION complicates 8-10% of all pregnancies, generally after 20 weeks of gestation. Gestational hypertension can be divided into several broad categories according to the complexity and associated symptoms, such as EDEMA; PROTEINURIA; SEIZURES; abnormalities in BLOOD COAGULATION and liver functions. | HYPERTENSION that develops as a result of PREGNANCY and regresses post partum. It is hypertension without PROTEINURIA or pathological EDEMA. [MeSH]
MedDRA Code 10070538
MeSH ID D046110; D046110; D046110
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
PIH Pregnancy induced hypertension | Pregnancy induced hypertension | Transient hypertension of pregnancy | Transient hypertension of pregnancy, antepartum | Transient hypertension of pregnancy, postpartum | Transient hypertension of pregnancy, unspecified as to episode of care | Transient hypertension of pregnancy, with delivery | Transient hypertension of pregnancy, with delivery, with mention of postpartum complication | Gestational hypertension | Hypertension, Pregnancy-Induced | Hypertension, Pregnancy Induced | Pregnancy-Induced Hypertension | Pregnancy Induced Hypertension | Hypertensions, Pregnancy Induced | Induced Hypertension, Pregnancy | Induced Hypertensions, Pregnancy | Gestational Hypertension | Hypertension, Gestational | Transient Hypertension, Pregnancy | Hypertension, Pregnancy Transient | Pregnancy Transient Hypertension
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00195Azathioprine0.002154%
BADD_D00501Clonazepam0.000259%
BADD_D00551Cyclosporine0.000519%
BADD_D00932Fluoxetine0.000363%
BADD_D00952Folic acid0.000588%
BADD_D01106Hydroxyprogesterone--
BADD_D01107Hydroxyprogesterone caproate-
BADD_D01265Levetiracetam0.000952%
BADD_D01401Metformin0.000026%
BADD_D01449Metronidazole0.000104%
BADD_D01566Nifedipine0.000336%
BADD_D01617Ondansetron0.000499%
BADD_D01834Prednisone0.000040%
BADD_D01888Quetiapine0.001019%
BADD_D02105Tacrolimus0.002839%
BADD_D02459Dalteparin0.012704%
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