Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Skin hypopigmentation
ADR ID BADD_A04043
ADR Hierarchy
23      Skin and subcutaneous tissue disorders
23.05      Pigmentation disorders
23.05.02      Hypopigmentation disorders
23.05.02.003      Skin hypopigmentation
Description A disorder characterized by loss of skin pigment (e.g., vitiligo). [CTCAE] A condition caused by a deficiency or a loss of melanin pigmentation in the epidermis, also known as hypomelanosis. Hypopigmentation can be localized or generalized, and may result from genetic defects, trauma, inflammation, or infections. [MeSH]
MedDRA Code 10040868
MeSH ID D017496
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Skin hypopigmentation | Hypomelanosis | Decreased skin pigmentation | Hypopigmentation | Hypomelanoses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01420Methoxsalen--
BADD_D01431Methylphenidate--
BADD_D01434Methylprednisolone acetate--
BADD_D01436Methylprednisolone sodium succinate--
BADD_D01491Mometasone furoate--
BADD_D01687Pazopanib0.002149%
BADD_D01688Pazopanib hydrochloride--
BADD_D01821Pramoxine hydrochloride--
BADD_D01830Prednicarbate--
BADD_D01832Prednisolone acetate--
BADD_D01834Prednisone0.000020%
BADD_D02100Sunitinib0.000381%
BADD_D02160Terbinafine0.000149%
BADD_D02236Tofacitinib0.000362%
BADD_D02272Triamcinolone acetonide0.000685%
BADD_D02273Triamcinolone diacetate--
BADD_D02274Triamcinolone hexacetonide--
BADD_D02450Crisaborole0.003316%
BADD_D02483Ribociclib0.000381%
BADD_D02515Pexidartinib0.000381%
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