Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02032Sodium acetate--
BADD_D02037Sodium cation--
BADD_D02038Sodium ferric gluconate complex--
BADD_D02039Sodium fluoride--
BADD_D02045Sodium nitrite--
BADD_D02047Sodium oxybate0.062313%
BADD_D02053Sofosbuvir0.203085%
BADD_D02054Solifenacin succinate--
BADD_D02055Somatropin--
BADD_D02056Somatuline depot--
BADD_D02057Sonidegib phosphate--
BADD_D02058Sorafenib0.029292%
BADD_D02060Sotalol--
BADD_D02061Sotalol hydrochloride--
BADD_D02066Spironolactone--
BADD_D02068Stavudine--
BADD_D02069Stiripentol--
BADD_D02078Succimer--
BADD_D02091Sulfamethoxazole--
BADD_D02096Sulfur hexafluoride--
BADD_D02097Sulindac--
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02100Sunitinib0.090225%
BADD_D02101Sunitinib malate--
BADD_D02104Tacrine hydrochloride--
BADD_D02105Tacrolimus--
BADD_D02106Tadalafil--
BADD_D02107Tafamidis0.064979%
BADD_D02111Tamoxifen--
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ADReCS-Target
ADR Term Drug Name Target