Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00998Gallium cation--
BADD_D01000Gallium nitrate--
BADD_D01003Ganciclovir--
BADD_D01004Ganciclovir sodium--
BADD_D01006Gatifloxacin--
BADD_D01007Gazyva--
BADD_D01008Gefitinib--
BADD_D01009Gemcitabine0.000616%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01012Gemfibrozil--
BADD_D01013Gemifloxacin--
BADD_D01014Gemifloxacin mesylate--
BADD_D01015Gemtuzumab ozogamicin--
BADD_D01021Glatiramer acetate--
BADD_D01022Gliclazide--
BADD_D01024Glipizide--
BADD_D01029Glutamine0.016818%
BADD_D01032Glycerol phenylbutyrate0.016818%
BADD_D01034Glycopyrrolate--
BADD_D01035Golimumab--
BADD_D01036Gonadorelin--
BADD_D01038Goserelin--
BADD_D01039Goserelin acetate--
BADD_D01040Granisetron0.095837%
BADD_D01041Granisetron hydrochloride--
BADD_D01043Guaifenesin0.000205%
BADD_D01044Guanabenz acetate--
BADD_D01046Guanfacine0.000554%
BADD_D01047Guanfacine hydrochloride--
BADD_D01051Halobetasol--
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