Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Gemfibrozil
Drug ID BADD_D01012
Description Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications.[L8525] Gemfibrozil was granted FDA approval on 21 December 1981.[L8525]
Indications and Usage For treatment of adult patients with very high elevations of serum triglyceride levels (types IV and V hyperlipidemia) who are at risk of developing pancreatitis (inflammation of the pancreas) and who do not respond adequately to a strict diet.
Marketing Status Prescription; Discontinued
ATC Code C10AB04
DrugBank ID DB01241
KEGG ID D00334
MeSH ID D015248
PubChem ID 3463
TTD Drug ID D05VIX
NDC Product Code 51655-143; 50268-350; 71335-0515; 66267-436; 65862-624; 72578-066; 55700-493; 68071-1733; 63187-146; 68071-2387; 50090-2902; 68788-7964; 43063-921; 70518-1563; 31722-128; 71205-169; 65691-0089; 63187-772; 61919-968; 70771-1431; 71610-601; 76282-225; 60687-224; 16571-784; 49452-3263; 59762-0737; 68071-2422; 71335-0899; 65862-424; 0071-0737; 70934-466; 72865-186; 43063-745; 0615-8354; 50090-5808; 71335-2025; 71610-200; 57237-163; 71335-1902; 71335-0971; 16714-101; 15440-1025; 43602-452; 71335-1996; 71610-107; 62991-2883; 68382-553; 70934-255; 68788-6447; 69097-821; 53002-2068; 71209-008; 75834-131; 43744-181; 42806-260; 53002-1068; 66651-905; 71335-0051; 61919-967; 68071-4053; 24658-260; 68071-2296
Synonyms Gemfibrozil | Gemfibrosil | Ausgem | Bolutol | Chem mart Gemfibrozil | CI-719 | CI 719 | CI719 | DBL Gemfibrozil | Decrelip | Gemfi 1A Pharma | Gemfibrozilo Bayvit | Bayvit, Gemfibrozilo | Gemfibrozilo Bexal | Gemfibrozilo Ur | Gemhexal | Gen-Gemfibrozil | Gen Gemfibrozil | GenGemfibrozil | GenRX Gemfibrozil | Gemfibrozil, GenRX | Healthsense Gemfibrozil | Gemfibrozil, Healthsense | Jezil | Lipazil | Lipox Gemfi | Litarek | Lopid | Lipur | Lopid R | Novo-Gemfibrozil | Novo Gemfibrozil | Nu-Gemfibrozil | Nu Gemfibrozil | NuGemfibrozil | Pilder | PMS-Gemfibrozil | PMS Gemfibrozil | SBPA Gemfibrozil | Gemfibrozil, SBPA | Terry White Chemists Gemfibrozil | Trialmin | Apo-Gemfibrozil | Apo Gemfibrozil | ApoGemfibrozil
Chemical Information
Molecular Formula C15H22O3
CAS Registry Number 25812-30-0
SMILES CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.000690%Not Available
Abdominal distension07.01.04.0010.000460%
Abdominal pain07.01.05.0020.000920%
Abdominal pain upper07.01.05.003--
Alanine aminotransferase increased13.03.01.0030.000460%
Alopecia23.02.02.0010.000460%
Anaemia01.03.02.0010.000460%
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Appendicitis11.01.07.001; 07.19.01.001--
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.01.0060.000460%
Asthenia08.01.01.0010.001149%Not Available
Atrial fibrillation02.03.03.002--
Blood bilirubin increased13.03.01.008--
Blood cholesterol increased13.12.01.0020.000460%
Blood creatine phosphokinase increased13.04.01.0010.000460%
Cataract06.06.01.001--
Cerebral haemorrhage24.07.04.001; 17.08.01.003--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.0110.000690%Not Available
Cholecystitis09.03.01.001--
Cholelithiasis09.03.01.0020.000460%Not Available
Chromaturia20.02.01.0020.000690%
Colitis07.08.01.001--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Cough22.02.03.001--
Depression19.15.01.0010.000460%
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