Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Guanabenz acetate
Drug ID BADD_D01044
Description An alpha-2 selective adrenergic agonist used as an antihypertensive agent. [PubChem]
Indications and Usage For management of High blood pressure
Marketing Status Prescription; Discontinued
ATC Code Not Available
DrugBank ID DB00629
KEGG ID D00605
MeSH ID D006143
PubChem ID 5702062
TTD Drug ID D0L4HY
NDC Product Code 86036-002
Synonyms Guanabenz | 2,6-Dichlorobenzylideneaminoguanidine | 2,6 Dichlorobenzylideneaminoguanidine | Guanabenz Acetate | Acetate, Guanabenz | Guanabenz Monoacetate | Monoacetate, Guanabenz | Wytensin | Wyeth-Ayerst of Guanabenz Acetate | Acetate Wyeth-Ayerst, Guanabenz | Guanabenz Acetate Wyeth-Ayerst | Wyeth Ayerst of Guanabenz Acetate | BR-750 | BR 750 | BR750 | WY-8678 | WY 8678 | WY8678
Chemical Information
Molecular Formula C10H12Cl2N4O2
CAS Registry Number 23256-50-0
SMILES CC(=O)O.C1=CC(=C(C(=C1)Cl)C=NN=C(N)N)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain upper07.01.05.003--
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Constipation07.02.02.001--
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Gynaecomastia21.05.04.003; 05.05.02.003--
Headache17.14.01.001--
Libido decreased21.03.02.005; 19.08.03.001--
Myalgia15.05.02.001--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Oedema08.01.07.006; 14.05.06.010--Not Available
Pain in extremity15.03.04.010--
Palpitations02.01.02.003--
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Sedation17.02.04.005--Not Available
Sexual dysfunction21.03.02.003; 19.08.05.002--Not Available
Sleep disorder19.02.04.001--Not Available
Somnolence17.02.04.006; 19.02.05.003--
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