Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Halobetasol
Drug ID BADD_D01051
Description Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047]
Indications and Usage For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Marketing Status Prescription; Discontinued
ATC Code D07AC21
DrugBank ID DB00596
KEGG ID D08660
MeSH ID C064466
PubChem ID 5311167
TTD Drug ID D00XPC
NDC Product Code Not Available
Synonyms halobetasol | ulobetasol | Ultravate | halobetasol propionate | 6 alpha-fluoroclobetasol 17-propionate | 6-fluoroclobetasol 17-propionate | CGP 14 458 | CGP-14458 | CGP 14458
Chemical Information
Molecular Formula C22H27ClF2O4
CAS Registry Number 98651-66-2
SMILES CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C)F
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Akathisia19.06.02.006; 17.01.02.002--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anxiety19.06.02.002--
Breast engorgement21.05.05.002; 18.08.02.001--Not Available
Breast pain21.05.05.003--
Bronchospasm22.03.01.004; 10.01.03.012--
Cataract06.06.01.001--
Catatonia19.11.01.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Death08.04.01.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis acneiform23.02.01.004--
Dermatitis contact10.01.01.003; 23.03.04.004; 12.03.01.040--Not Available
Diarrhoea07.02.01.001--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Electrocardiogram abnormal13.14.05.001--Not Available
Electrocardiogram QT prolonged13.14.05.004--
Emotional disorder19.04.02.005--Not Available
Erythema23.03.06.001--Not Available
Euphoric mood19.04.02.006--
Extrapyramidal disorder17.01.02.007--
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