Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxygen
Drug ID BADD_D02471
Description Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.
Indications and Usage Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia [L745] to reduce the extent of hypoxia-induced tissue damage and malfunction.
Marketing Status Not Available
ATC Code V03AN01
DrugBank ID DB09140
KEGG ID D00003
MeSH ID D010100
PubChem ID 977
TTD Drug ID Not Available
NDC Product Code 71408-001; 76091-002; 49154-001; 55703-001; 62377-001; 53952-001; 11928-002; 62671-001; 52568-001; 43621-001; 60367-002; 64395-0001; 57999-001; 72760-001; 68623-123; 59387-001; 51319-072; 53663-0001; 62066-001; 49221-0030; 66083-741; 82401-001; 60768-001; 51486-720; 67061-001; 62234-001; 51319-073; 61865-001; 62686-001; 55913-001; 73055-001; 60596-1072; 56130-002; 61830-001; 49204-001; 72457-003; 10297-001; 44517-001; 42821-001; 11054-009; 29181-001; 62481-4565; 61420-0001; 20942-672; 69024-001; 62914-1000; 19218-0005; 58049-123; 69216-001; 70951-123; 54451-001; 59788-001; 45405-001; 70323-123; 72661-123; 19218-0002; 67525-100; 59247-001; 63674-001; 65603-100; 65336-001; 19218-0004; 62118-001; 73266-001; 59087-001; 14214-0123; 62486-130; 63560-001; 72692-123; 66586-1073; 69534-001; 60568-123; 58722-9094; 64075-123; 10482-002; 10412-0001; 39313-001; 68877-001; 10073-111; 61776-0001; 58632-001; 25373-001; 54182-001; 10526-005; 65077-001; 65297-001; 80268-001; 72746-0001; 62273-001; 72807-001; 81313-001; 63970-001; 52698-001; 44076-010; 15055-001; 60980-002; 61398-0828; 55728-100; 48546-0006; 51475-001; 81734-001; 50153-110; 55151-123; 51887-720; 14080-001; 63144-001; 46123-001; 58089-001; 49575-001; 42068-001; 61362-2150; 58700-001; 49479-722; 66228-001; 61426-123; 19218-0001; 65386-0001; 57957-0007; 69241-001; 11988-001; 58125-0001; 24887-001; 13826-001; 52374-011; 60971-1176; 46123-045; 62715-0001; 73012-001; 61128-001; 62179-1234; 59579-001; 19218-0008; 10698-0001; 64140-101; 55785-123; 52374-101; 19979-000; 80792-001; 63862-011; 67932-1313; 48546-0002; 66754-001; 54316-123; 20703-002; 67573-0104; 10942-2001; 62598-001; 68769-002; 72574-001; 76349-001; 81676-001; 76831-001; 49798-001; 67905-0001; 42914-001; 70097-001; 11324-721; 51051-003; 11401-6994; 17575-001; 10690-001; 58247-001; 72817-001; 44363-1815; 80421-100; 58128-0001; 62097-9937; 50505-001; 73468-005; 63553-001; 19218-0009; 50699-1072; 54706-0001; 67477-001; 66890-990; 65868-001; 23650-001; 63418-0001; 13859-001; 54202-001; 60779-001; 43734-002; 50322-005; 52003-011; 66767-999; 55858-001; 73422-001; 72713-123; 62447-0011; 54384-1073; 69075-001; 60184-001; 64545-0001; 52374-001; 59842-012; 10221-001; 58755-0001; 62581-1234; 19218-0006; 50597-001; 72987-001; 43734-001; 53854-123; 72814-001; 10492-001; 73037-001; 72995-001; 49799-001; 73078-001; 20479-0682; 59378-001; 80650-001; 42602-001; 60833-001; 66503-001; 64952-002; 60849-123; 61580-123; 81681-001; 21220-119; 64464-001; 63138-120; 63978-001; 73073-001; 40097-001; 71227-001; 70313-001; 70291-1000; 58662-0001; 43713-001; 68317-001; 72908-001; 54619-0001; 72710-123; 76056-001; 55037-113; 53425-001; 67711-001; 42887-001; 61903-001; 70300-001; 72973-001; 72637-001; 58722-9093; 54832-0001; 68794-001; 61869-0001; 54218-500; 58878-001; 65010-001; 11324-001; 66961-100; 66345-001; 24312-001; 20175-072; 26866-001; 59336-001; 68540-001; 31462-001; 62371-1234; 66487-001; 18482-018; 55322-0001; 73087-001; 19218-0003; 34940-004; 65208-123; 63173-001; 46123-002; 73093-001; 72706-123; 60560-1072; 70977-001; 81700-001; 64097-0001; 42241-001; 72862-001; 81287-001; 59924-001; 51960-001; 73543-001; 55050-0011; 64203-020; 64920-0001; 52142-001; 59522-001; 11056-001; 50063-001; 72662-123; 69286-001; 10218-001; 68796-5626; 52346-013; 65464-001; 49653-003; 44356-0001; 67506-001; 82007-000; 65257-001; 14784-001
Synonyms Oxygen | Oxygen-16 | Oxygen 16 | Dioxygen
Chemical Information
Molecular Formula O2
CAS Registry Number 7782-44-7
SMILES O=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Emphysema22.01.02.0020.003042%Not Available
Encephalopathy17.13.02.0010.008747%
Epilepsy17.12.03.0020.005831%Not Available
Erythema23.03.06.0010.005831%Not Available
Erythromelalgia24.03.01.001; 23.06.05.0020.008747%Not Available
Fatigue08.01.01.002--
Foot fracture15.08.03.012; 12.04.01.0120.008747%Not Available
Generalised tonic-clonic seizure17.12.01.0020.008747%Not Available
Haemoglobin decreased13.01.05.0030.008747%Not Available
Heart rate increased13.14.04.0020.005831%Not Available
Hypercapnia22.02.02.002; 14.01.04.0010.014578%Not Available
Hyperhidrosis23.02.03.004; 08.01.03.0280.014578%
Hypokalaemia14.05.03.0020.008747%
Hypokinesia17.01.02.0090.005831%Not Available
Hypotension24.06.03.0020.017494%
Hypoxia22.02.02.0030.043734%
Infection11.01.08.0020.002282%Not Available
Interstitial lung disease22.01.02.003; 10.02.01.0330.005831%Not Available
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.0040.003803%Not Available
Lactic acidosis14.01.01.0020.005831%Not Available
Leukocytosis01.02.01.0020.005831%
Lip oedema23.04.01.006; 10.01.05.004; 07.05.04.0040.005831%Not Available
Lung disorder22.02.07.0010.003803%Not Available
Malaise08.01.01.0030.017494%
Memory impairment19.20.01.003; 17.03.02.0030.005831%
Myocardial infarction24.04.04.009; 02.02.02.007--
Myopia06.02.04.0020.008747%Not Available
Neoplasm malignant16.16.01.0010.001521%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.0070.005831%
Oxygen saturation decreased13.02.01.0040.040818%Not Available
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