Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Chlorpheniramine
Drug ID BADD_D02400
Description A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Indications and Usage Not Available
Marketing Status Not Available
ATC Code R06AB04
DrugBank ID DB01114
KEGG ID D07398
MeSH ID D002744
PubChem ID 2725
TTD Drug ID D0B7NG
NDC Product Code Not Available
Synonyms Chlorpheniramine | Chlorprophenpyridamine | Chlorphenamine | Aller-Chlor | Antihistaminico Llorens | Chlor-100 | Chlor-Trimeton | Cloro-Trimeton | Chlorpheniramine Maleate | Maleate, Chlorpheniramine | Chlorpheniramine Tannate | Tannate, Chlorpheniramine | Chlorpro | Chlorspan 12 | Chlortab-4 | Efidac 24 | Kloromin | Piriton | Teldrin | Chlo-Amine | Chlor-Tripolon
Chemical Information
Molecular Formula C16H19ClN2
CAS Registry Number 113-92-8
SMILES CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction24.06.03.006; 10.01.07.0010.003195%
Cardiac arrest02.03.04.0010.002130%
Coma17.02.09.0010.002130%Not Available
Death08.04.01.001--
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.0070.003195%
Drug abuse19.07.02.0100.001111%Not Available
Drug dependence19.07.02.0090.002130%Not Available
Drug hypersensitivity10.01.01.0010.002130%Not Available
Drug withdrawal syndrome19.07.02.011; 08.06.02.0040.002130%Not Available
Erythema multiforme23.03.01.003; 10.01.03.0150.002130%
Hypersensitivity10.01.03.0030.002130%
Hypotension24.06.03.0020.005325%
Loss of consciousness17.02.04.0040.002130%Not Available
Mania19.16.02.0020.002130%
Nervous system disorder17.02.10.0010.002130%Not Available
Respiratory distress22.02.01.0120.000556%Not Available
Rib fracture15.08.07.001; 12.04.07.0010.002130%Not Available
Somnolence19.02.05.003; 17.02.04.0060.002130%
Tachycardia02.03.02.0070.003195%Not Available
Torsade de pointes02.03.04.0050.002130%Not Available
Toxic epidermal necrolysis10.01.01.006; 23.03.01.008; 12.03.01.015; 11.07.01.0060.000556%
Cervical vertebral fracture15.08.05.002; 12.04.04.0030.000556%Not Available
Contusion24.07.06.001; 23.03.11.002; 15.03.01.008; 12.01.06.0010.002130%
Bipolar disorder19.16.01.0030.002130%Not Available
Drowning12.01.03.008; 08.04.01.0140.000556%Not Available
Fractured coccyx15.08.05.005; 12.04.04.0050.002130%Not Available
Accidental death12.01.08.040; 08.04.01.0130.000834%Not Available
The 1th Page    1    Total 1 Pages