Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Triamcinolone acetonide
Drug ID BADD_D02272
Description Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses.[L8249] Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate.[L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957.[L8243] In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval[L38973] - for the treatment of patients with macular edema associated with uveitis.[L38963]
Indications and Usage For the treatment of perennial and seasonal allergic rhinitis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A01AC01; C05AA12; D07AB09; D07XB02; H02AB08; R01AD11; R03BA06; S01BA05
DrugBank ID DB00620
KEGG ID D00983
MeSH ID D014222
PubChem ID 6436
TTD Drug ID Not Available
NDC Product Code 72189-277; 53002-9121; 0713-0676; 72603-108; 0065-0543; 49999-150; 62011-0320; 76420-162; 44118-711; 63629-8783; 68788-7814; 63187-214; 63629-8782; 70518-3373; 16714-150; 70121-1168; 41250-443; 68788-0149; 70121-1657; 68071-4168; 68071-2339; 41520-443; 63629-8708; 50090-1444; 33342-333; 68462-131; 68071-4397; 0713-0229; 59779-746; 22552-0032; 70121-1655; 70121-1651; 68071-2464; 16714-130; 70121-1652; 50090-2360; 68071-4630; 70518-1094; 67438-045; 0713-0225; 46439-8742; 71205-451; 71205-108; 63629-8778; 33342-331; 70518-0075; 12516-1510; 71565-040; 68071-4286; 52128-173; 0003-0293; 0703-0241; 0168-0003; 0168-0004; 51672-1284; 60432-560; 0703-0243; 68071-1623; 76420-085; 11822-0443; 0003-0494; 0703-0245; 63629-8456; 0168-0005; 49076-6701; 0713-0679; 49035-443; 68071-5070; 52565-011; 45802-045; 71205-124; 71161-135; 41167-5800; 63629-8785; 71205-627; 0316-0175; 71205-009; 66267-934; 35573-404; 70121-1049; 68788-7797; 45802-065; 53002-0150; 76420-220; 50090-4106; 68462-798; 71205-033; 76420-222; 45802-063; 51552-0033; 68071-4564; 24208-040; 21130-443; 12516-1509; 82298-123; 0713-0655; 45802-055; 71205-038; 41167-5900; 64380-871; 67877-317; 16714-140; 72189-039; 37808-443; 50090-2658; 52945-068; 50090-0819; 63187-025; 0003-0315; 50090-0295; 12516-1508; 50090-0162; 63629-8780; 0316-0165; 63629-8779; 0713-0228; 36800-621; 55910-280; 70518-2403; 33342-332; 74157-901; 68071-2516; 72603-202; 68071-2294; 11673-717; 63629-8781; 0363-0811; 60722-3012; 0316-0170; 64380-870; 45802-109; 0168-0002; 33342-328; 67877-251; 66267-933; 68788-7048; 51672-1335; 0168-0006; 70752-130; 0113-0443; 69842-244; 63187-495; 53002-9130; 59088-733; 61919-650; 63629-2407; 70121-1169; 68071-2362; 52565-010; 53002-9330; 63187-661; 45802-049; 67877-318; 46122-385; 76003-1145; 50090-3522; 72603-401; 10631-093; 0113-7005; 30142-443; 52565-056; 76420-203; 52817-811; 63629-8841; 68071-4391; 50090-2542; 68788-7501; 50090-0293; 68788-9172; 46287-010; 53002-0151; 70529-048; 63981-443; 50090-3802; 45802-064; 70121-1654; 33342-329; 45802-817; 50090-0256; 46439-8730; 45802-054; 63629-8707; 53002-9120; 33342-327; 63629-2406; 51927-0134; 64980-320; 70518-2393; 65089-0008; 68071-1803; 51672-1282; 49452-7900; 50090-0362; 52565-014; 0713-0226; 38779-0011; 70121-1653; 68788-7506; 68462-797; 57582-018; 51672-1267; 42571-385; 63187-870; 61919-594; 69256-443; 53002-9333; 59088-843; 50090-3754; 70000-0204; 53002-9334; 62991-1156; 70752-129; 46439-8703; 72288-443; 68071-2361; 70518-2285; 61919-619; 68071-1872; 30142-813; 70518-2938; 24470-922; 68071-4383; 52565-048; 45865-898; 60432-561; 49999-216; 53002-9331; 64980-429; 63275-9943; 70518-2963; 53002-9770; 64380-901; 41163-443; 40032-097; 51862-290; 0713-0766; 68071-4561; 63187-053
Synonyms Triamcinolone Acetonide | Acetonide, Triamcinolone | Cinonide | Tricort-40 | Tricort 40 | Tricort40 | Kenalog | Kenalog 40 | Azmacort | Kenacort A
Chemical Information
Molecular Formula C24H31FO6
CAS Registry Number 76-25-5
SMILES CC1(OC2CC3C4CCC5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Panophthalmitis06.04.05.005--Not Available
Papilloedema17.07.02.004; 24.03.07.001; 06.09.02.002--
Paraesthesia17.02.06.005--
Paraparesis17.01.04.006--Not Available
Paraplegia17.01.04.007--Not Available
Pathological fracture15.08.02.008; 12.04.02.006; 16.32.03.007--Not Available
Peptic ulcer07.04.07.001--Not Available
Personality change19.05.01.006; 17.02.05.019--
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Photosensitivity reaction23.03.09.003--
Pruritus23.03.12.001--
Pulmonary congestion24.03.08.001; 22.01.03.002; 02.05.02.002--Not Available
Pulmonary oedema02.05.02.003; 22.01.03.003--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyoderma23.09.01.007; 11.01.12.009--Not Available
Pyrexia08.05.02.003--
Quadriplegia17.01.04.013--Not Available
Rash23.03.13.001--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Rhinitis perennial22.04.04.006; 10.01.04.007--Not Available
Rhinorrhoea22.02.05.010--
Rosacea23.02.08.001--Not Available
Secondary adrenocortical insufficiency14.11.01.014; 05.01.02.003--Not Available
Seizure17.12.03.001--
Sensory disturbance17.02.07.006--Not Available
Shock24.06.02.002--Not Available
Sinus congestion22.04.06.001--Not Available
Sinusitis22.07.03.007; 11.01.13.005--
Skin atrophy23.01.05.001--
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