Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Ropivacaine hydrochloride
Drug ID BADD_D01968
Description Ropivacaine is an aminoamide local anaesthetic drug commonly marketed by AstraZeneca under the trade name Naropin. It is present as a racemic mixture of the enantiomers containing equal proportions of the “S” and “R” forms. The marketed form contains the single S-enantiomer as the active ingredient.
Indications and Usage Used in obstetric anesthesia and regional anesthesia for surgery.
Marketing Status approved
ATC Code N01BB09
DrugBank ID DB00296
KEGG ID D04048
MeSH ID D000077212
PubChem ID 175804
TTD Drug ID D09RHQ
NDC Product Code 25021-671; 55150-197; 68083-263; 0409-9300; 70121-1734; 51552-1590; 0143-9263; 52584-286; 55150-201; 63323-286; 63323-288; 70069-063; 70121-1733; 70121-1735; 61876-0071; 43066-027; 0404-9924; 70069-067; 55150-196; 63323-285; 0409-9302; 70069-061; 70121-1732; 72572-707; 55150-200; 65145-107; 65145-108; 0409-9301; 70069-062; 76339-124; 17478-082; 43066-023; 0143-9266; 48954-722; 25021-652; 68083-262; 46014-1058; 49452-6303; 65372-1159; 17478-081; 0409-9303; 70069-064; 49386-025; 43066-015; 43066-019; 55150-198; 63323-287; 65145-109; 65145-110; 70069-065; 70069-066; 0143-9264; 0143-9265; 55150-195; 55150-199
UNII V910P86109
Synonyms Ropivacaine | 1-Propyl-2',6'-pipecoloxylidide | 1 Propyl 2',6' pipecoloxylidide | Naropin | Ropivacaine Monohydrochloride | Ropivacaine Hydrochloride | AL 381 | AL-381 | AL381 | Naropeine | LEA 103 | LEA-103 | LEA103 | Ropivacaine Monohydrochloride, (S)-isomer
Chemical Information
Molecular Formula C17H27ClN2O
CAS Registry Number 98717-15-8
SMILES CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Erythema23.03.06.001--Not Available
Extrasystoles02.03.02.003--Not Available
Eyelid ptosis17.17.02.004; 06.05.01.002--Not Available
Failed trial of labour18.07.03.002--Not Available
Feeling abnormal08.01.09.014--Not Available
Fever neonatal18.04.01.009; 08.05.02.007--Not Available
Foetal distress syndrome18.03.02.003--Not Available
Gastrointestinal pain07.01.05.005--
Generalised tonic-clonic seizure17.12.01.002--Not Available
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Hallucination19.10.04.003--
Headache17.14.01.001--
Heart disease congenital02.11.01.014; 03.07.07.001--Not Available
Hepatic function abnormal09.01.02.001--Not Available
Horner's syndrome17.05.01.004; 16.32.03.006; 06.09.04.002--Not Available
Hypercapnia22.02.02.002; 14.01.04.001--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkalaemia14.05.03.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Hypocalcaemia14.04.01.004--
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypoglycaemia neonatal18.04.06.003; 14.06.03.006; 05.06.03.006--Not Available
Hypokalaemia14.05.03.002--
Hypokinesia17.01.02.009--Not Available
Hypomagnesaemia14.04.02.001--
Hypoproteinaemia14.10.01.003; 09.01.02.004--Not Available
Hypotension24.06.03.002--
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