Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methazolamide
Drug ID BADD_D01410
Description A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Indications and Usage For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma
Marketing Status Prescription; Discontinued
ATC Code S01EC05
DrugBank ID DB00703
KEGG ID D00655
MeSH ID D008704
PubChem ID 4100
TTD Drug ID D0C2II
NDC Product Code 42571-239; 0574-0790; 42571-240; 62559-240; 51407-026; 55806-021; 72969-047; 63629-1986; 50090-3233; 11712-530; 69575-4008; 63629-1958; 0574-0791; 62559-241; 48954-472; 68682-022; 11712-007; 71052-045; 68682-023; 51407-027; 63629-1987; 55806-020
Synonyms Methazolamide | N-Methylacetazolamide | N Methylacetazolamide
Chemical Information
Molecular Formula C5H8N4O3S2
CAS Registry Number 554-57-4
SMILES CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pancytopenia01.03.03.003--Not Available
Paraesthesia17.02.06.005--
Paralysis17.01.04.004--Not Available
Photosensitivity reaction23.03.09.003--
Polyuria20.02.03.002--Not Available
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.03.020--
Thrombocytopenic purpura23.06.01.007; 01.08.01.003--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.006--
Urticaria23.04.02.001; 10.01.06.001--
Vertigo04.04.01.003; 17.02.12.002--
Vomiting07.01.07.003--
Hypoacusis04.02.01.006--
Urine output increased13.13.03.002--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
Blood disorder01.05.01.004--Not Available
Bone marrow failure01.03.03.005--
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